HUNK and RABEP1

Number of citations of the paper that reports this interaction (PMID 11129044)
3

Data Source:
HPRD (two hybrid)

		HUNK	RABEP1
Gene Name		hormonally up-regulated Neu-associated kinase	rabaptin, RAB GTPase binding effector protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Endosome Early Endosome Endocytic Vesicle Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Homodimerization Activity
	Biological Process	Protein Phosphorylation Signal Transduction Multicellular Organismal Development	Endocytosis Apoptotic Process Protein Transport Positive Regulation Of GTPase Activity Membrane Fusion
Pathways
Drugs
Diseases
GWAS		Reasoning ( 21107309) Type 2 diabetes ( 21490949) Vitiligo ( 19890347)
Protein-Protein Interactions		2 interactors: LNX1 RABEP1	22 interactors: AP1G1 AP1G2 ATXN7 CASP3 CCND1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 ITSN2 RAB1A RAB33B RAB4A RAB5A RABGEF1 RGS17 TRIM26 TSC2 UBC YWHAG
Entrez ID		30811	9135
HPRD ID		09410	04684
Ensembl ID		ENSG00000142149	ENSG00000029725
Uniprot IDs		P57058	F5H355 Q15276
PDB IDs			1P4U 1TU3 1X79
Enriched GO Terms of Interacting Partners?			Intracellular Protein Transport Intracellular Transport Establishment Of Localization In Cell Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Cellular Localization Protein Localization Transport Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport Membrane Organization Positive Regulation Of Metabolic Process Regulation Of Exocytosis Regulation Of Phosphorylation Intracellular Signal Transduction Endocytosis Regulation Of Endocytosis Negative Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Catalytic Activity Neurotrophin TRK Receptor Signaling Pathway Ras Protein Signal Transduction Neurotrophin Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Negative Regulation Of Transferase Activity Signal Transduction Negative Regulation Of Protein Phosphorylation Regulation Of Signaling Regulation Of Cellular Component Organization Small GTPase Mediated Signal Transduction Virion Assembly Positive Regulation Of Hydrolase Activity Apoptotic Signaling Pathway Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Cytoplasmic Transport Signaling Regulation Of Metabolic Process Positive Regulation Of GTPase Activity Regulation Of Signal Transduction Cellular Response To Stimulus Cell Communication Regulation Of Protein Kinase Activity Negative Regulation Of Signaling Negative Regulation Of Exocytosis Protein Targeting
Tagcloud ?		autophagy beneficial combat contributes crosstalk drive exists fail her2 impacts impairing impairs initiated lapatinib maintain mechanistically modulation neu observation overcoming prevent promoting receive resistant supported therapeutically trastuzumab tumorigenesis uncover	adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples gga1 golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically reach sense tgn traffic trafficking transmembrane tubular whereby
Tagcloud (Difference) ?		autophagy beneficial combat contributes crosstalk drive exists fail her2 impacts impairing impairs initiated lapatinib maintain mechanistically modulation neu observation overcoming prevent promoting receive resistant supported therapeutically trastuzumab tumorigenesis uncover	adpkd arl3 autosomal cilia ciliary ciliopathies cleaved couples gga1 golgi gps localize milieu module must pc1 pc2 polycystic polycystin proper proteolytically reach sense tgn traffic trafficking transmembrane tubular whereby
Tagcloud (Intersection) ?