HUNK and N4BP2L2

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		HUNK	N4BP2L2
Description		hormonally up-regulated Neu-associated kinase	NEDD4 binding protein 2 like 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Transcription Repressor Complex Extracellular Exosome
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Transcription Corepressor Activity Protein Binding Enzyme Binding
	Biological Process	Signal Transduction Intracellular Signal Transduction	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Blastocyst Development Positive Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 32581322) Joint damage progression in ACPA-negative rheumatoid arthritis ( 26077402) LDL cholesterol levels in HIV infection ( 33109212) Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309) Type 2 diabetes ( 21490949) Vitiligo ( 19890347)	Adult body size ( 32376654) Breast cancer ( 23535729) Coronary artery disease ( 29212778 33020668) Heel bone mineral density ( 30598549) LDL cholesterol ( 30275531) Logical memory (delayed recall) ( 29274321) Myocardial infarction ( 33532862)
Interacting Genes		92 interacting genes: AARS1 ABLIM1 ACTR8 AGAP3 AIP AKAP8L AKR1C3 ALAD ANXA7 APBA2 APPL2 ARMCX4 ASCL1 ASPA ATP5F1B BIN1 CAMK1 CCAR1 CLU COG2 COPA COPS4 COPS5 CTDSP1 CTR9 CXXC5 DIS3L DLAT DLST DNAJA1 DST EEF1A2 EFNA1 EIF4G1 EPRS1 GEN1 HEATR6 HEY1 IFT81 IFT88 KDM6A KIF3A LIMK1 LNX1 LRSAM1 LURAP1 MAGED1 MBD1 MCHR1 MGAT5B MOAP1 MORF4L2 MTMR10 MYCBP2 N4BP2L2 NAPA NEUROD2 OLR1 PICK1 PITHD1 PPP1R16B PTPRA PTPRD RAB5B RABEP1 SH2B1 SLC6A1 SMARCE1 SMYD2 SNRNP48 SNRNP70 SORBS1 SPARCL1 STMN1 STUB1 TAF1 TOMM6 TRIM68 TTC28 UBE2O USP8 VCPIP1 VPS35L VSNL1 ZBTB44 ZNF197 ZNF292 ZNF343 ZNF655 ZNF662 ZNF76 ZNF793	7 interacting genes: HOXA1 HUNK LMO2 NAA38 PPIA PPIH PPIL1
Entrez ID		30811	10443
HPRD ID		09410	15119
Ensembl ID		ENSG00000142149	ENSG00000244754
Uniprot IDs		P57058	A0A6I8PRE0 A0A6I8PRM1 A0A6I8PRR0 A0A6I8PS46 B4DPY1 Q6ZV26 Q92802
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Protein Catabolic Process Regulation Of Cellular Component Organization Negative Regulation Of Protein Metabolic Process Regulation Of DNA-templated Transcription Positive Regulation Of Cellular Component Organization Positive Regulation Of Amyloid Fibril Formation Protein Modification By Small Protein Conjugation Regulation Of RNA Biosynthetic Process DeNEDDylase Activity	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Peptidyl-prolyl Isomerization Cyclosporin A Binding Isomerase Activity Protein Folding Positive Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Semicircular Canal Formation Regulation Of Viral Genome Replication Abducens Nerve Formation Optokinetic Behavior Negative Regulation Of Protein K48-linked Ubiquitination NatC Complex Regulation Of Viral Life Cycle Cell Adhesion Molecule Production U4/U6 SnRNP U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Regulation Of Viral Process MRNA Metabolic Process Outer Ear Morphogenesis Embryonic Neurocranium Morphogenesis Virion Binding Regulation Of Protein K48-linked Ubiquitination Activation Of Protein Kinase B Activity Negative Regulation Of Viral Life Cycle Endothelial Cell Activation Heparan Sulfate Binding Negative Regulation Of Protein Polyubiquitination Negative Regulation Of Stress-activated Protein Kinase Signaling Cascade Negative Regulation Of Stress-activated MAPK Cascade MRNA Splicing, Via Spliceosome Spliceosomal Complex RNA Splicing, Via Transesterification Reactions Exoribonuclease Complex Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) TRAMP-dependent TRNA Surveillance Pathway TRNA Surveillance RRNA 3'-end Processing Nucleolar Exosome (RNase Complex) U4 SnRNA 3'-end Processing Nuclear Polyadenylation-dependent RRNA Catabolic Process TRNA Decay Nuclear MRNA Surveillance Nucleus RNA Processing Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity RRNA Catabolic Process Nuclear Exosome (RNase Complex)
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?