APIP and C6orf165

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		APIP	C6orf165
Gene Name		APAF1 interacting protein	chromosome 6 open reading frame 165
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Methylthioribulose 1-phosphate Dehydratase Activity
	Biological Process	Sulfur Amino Acid Metabolic Process Polyamine Metabolic Process Apoptotic Process L-methionine Biosynthetic Process From S-adenosylmethionine L-methionine Biosynthetic Process From Methylthioadenosine Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Apoptotic Process Small Molecule Metabolic Process Regulation Of ERK1 And ERK2 Cascade
Pathways		Metabolism of polyamines Sulfur amino acid metabolism Methionine salvage pathway Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cystic fibrosis severity ( 21602797)
Protein-Protein Interactions		17 interactors: APAF1 C6orf165 IMPDH2 LNX1 NIF3L1 NUDT18 PDZD4 PPP1CC PSMA1 SDCBP SKP1 TNPO2 TSC22D4 VIM VPS25 WDYHV1 ZBTB25	25 interactors: ADAMTSL4 AES APIP BANP C1orf94 CEP57L1 GFAP GLYR1 GPRASP2 GSE1 KLHL3 KRT31 KRT40 KRTAP13-1 LZTS2 MDFI RNF138 ROCK1 SAMD3 SOX30 TCF12 TFIP11 TMCC2 UBXN11 USHBP1
Entrez ID		51074	154313
HPRD ID		14725	12863
Ensembl ID		ENSG00000149089	ENSG00000272514
Uniprot IDs		J3KN82 Q96GX9	Q8IYR0 Q8N771
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Catabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition GDP Catabolic Process Response To G1 DNA Damage Checkpoint Signaling DGDP Catabolic Process DADP Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Proteolysis Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Regulation Of Ubiquitin-protein Transferase Activity Cellular Macromolecule Catabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Dihydrobiopterin Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly GMP Biosynthetic Process Positive Regulation Of Protein Ubiquitination Regulation Of Extracellular Vesicular Exosome Assembly Purine Ribonucleoside Diphosphate Catabolic Process Endosome Transport Via Multivesicular Body Sorting Pathway Nucleobase-containing Small Molecule Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Late Endosome To Vacuole Transport Viral Process G1/S Transition Of Mitotic Cell Cycle Bergmann Glial Cell Differentiation Ribonucleoside Diphosphate Catabolic Process Regulation Of Metabolic Process Protein Ubiquitination Circadian Rhythm Regulation Of Apoptotic DNA Fragmentation GMP Metabolic Process Nucleoside Diphosphate Catabolic Process Protein Modification By Small Protein Conjugation Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Deoxyribonucleoside Diphosphate Metabolic Process Regulation Of Protein Ubiquitination Substrate-dependent Cell Migration, Cell Extension Histone H2A Monoubiquitination
Tagcloud ?		11p12 14q24 6q12 9p24 abcd4 acyp1 amplifications cd109 cd274 commd9 coq6 cttn fjx1 hbld1 interscience jdp2 jpages ltbp2 myo6 otscc pdhx pinpointed ppfia1 q14 rln1 slc1a1 suppmat trim44 znf410
Tagcloud (Difference) ?		11p12 14q24 6q12 9p24 abcd4 acyp1 amplifications cd109 cd274 commd9 coq6 cttn fjx1 hbld1 interscience jdp2 jpages ltbp2 myo6 otscc pdhx pinpointed ppfia1 q14 rln1 slc1a1 suppmat trim44 znf410
Tagcloud (Intersection) ?