APIP and WDYHV1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		APIP	WDYHV1
Gene Name		APAF1 interacting protein	WDYHV motif containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Methylthioribulose 1-phosphate Dehydratase Activity	Protein Binding Protein-N-terminal Glutamine Amidohydrolase Activity
	Biological Process	Sulfur Amino Acid Metabolic Process Polyamine Metabolic Process Apoptotic Process L-methionine Biosynthetic Process From S-adenosylmethionine L-methionine Biosynthetic Process From Methylthioadenosine Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Apoptotic Process Small Molecule Metabolic Process Regulation Of ERK1 And ERK2 Cascade	Cellular Protein Modification Process
Pathways		Metabolism of polyamines Sulfur amino acid metabolism Methionine salvage pathway Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cystic fibrosis severity ( 21602797)
Protein-Protein Interactions		17 interactors: APAF1 C6orf165 IMPDH2 LNX1 NIF3L1 NUDT18 PDZD4 PPP1CC PSMA1 SDCBP SKP1 TNPO2 TSC22D4 VIM VPS25 WDYHV1 ZBTB25	88 interactors: ACTB ACTG1 AMOT AMOTL2 APIP ASL BIRC2 BLMH BLOC1S6 C1orf50 CAPN3 CBFA2T2 CCDC102B CCDC184 CDA CDR2 COIL CRYAA CTH DAB1 DCTPP1 DHPS EDARADD EIF2B1 ETV6 FTH1 GAS7 GMDS GNMT GOLGA2 HPRT1 HSD17B14 JUP KCNH1 KCTD1 KLHL12 KRT31 KRTAP10-5 KRTAP10-7 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LONRF1 LZTFL1 LZTS2 MAGEA11 MARCH10 MDFI MIF MTUS2 NCOA5 NECAB2 NME1 NPL NT5C1A NUDT14 PCBD1 PNMA1 PNMA5 PPCDC PRMT1 PRPS2 PTS PYGM RABAC1 RAD54L RBBP8 RBPMS RPIA SEPT3 SFN SIAH1 SMN1 STX11 THAP1 TMEM239 TNR TOLLIP TRIM27 TRIM54 TRIP13 TSC22D1 VAC14 VCP XIAP ZBTB8A ZNF341
Entrez ID		51074	55093
HPRD ID		14725	07653
Ensembl ID		ENSG00000149089	ENSG00000156795
Uniprot IDs		J3KN82 Q96GX9	Q96HA8
PDB IDs			3C9Q
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Catabolic Process Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition GDP Catabolic Process Response To G1 DNA Damage Checkpoint Signaling DGDP Catabolic Process DADP Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Proteolysis Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Regulation Of Ubiquitin-protein Transferase Activity Cellular Macromolecule Catabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Dihydrobiopterin Metabolic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly GMP Biosynthetic Process Positive Regulation Of Protein Ubiquitination Regulation Of Extracellular Vesicular Exosome Assembly Purine Ribonucleoside Diphosphate Catabolic Process Endosome Transport Via Multivesicular Body Sorting Pathway Nucleobase-containing Small Molecule Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Late Endosome To Vacuole Transport Viral Process G1/S Transition Of Mitotic Cell Cycle Bergmann Glial Cell Differentiation Ribonucleoside Diphosphate Catabolic Process Regulation Of Metabolic Process Protein Ubiquitination Circadian Rhythm Regulation Of Apoptotic DNA Fragmentation GMP Metabolic Process Nucleoside Diphosphate Catabolic Process Protein Modification By Small Protein Conjugation Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Deoxyribonucleoside Diphosphate Metabolic Process Regulation Of Protein Ubiquitination Substrate-dependent Cell Migration, Cell Extension Histone H2A Monoubiquitination	Protein Oligomerization Protein Complex Assembly Protein Homooligomerization Cellular Component Assembly Protein Homotetramerization Protein Tetramerization Nucleobase-containing Small Molecule Metabolic Process Nucleoside Metabolic Process Catabolic Process Cellular Nitrogen Compound Metabolic Process Purine Nucleoside Metabolic Process Anatomical Structure Development Small Molecule Metabolic Process Developmental Process Biosynthetic Process Cell Differentiation Nitrogen Compound Metabolic Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Apoptotic Process Cellular Metabolic Process Purine Nucleoside Monophosphate Catabolic Process Regulation Of Cell Death Tetrahydrobiopterin Biosynthetic Process Cell Development Nucleotide Metabolic Process System Development Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Ubiquitination Sulfur Amino Acid Metabolic Process Multicellular Organismal Development Aromatic Compound Catabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Modification By Small Protein Conjugation Cofactor Metabolic Process Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Neuron Projection Development Regulation Of Metabolic Process Organophosphate Metabolic Process Cellular Modified Amino Acid Metabolic Process Regulation Of Cellular Localization Membrane Organization Response To Stimulus Organophosphate Catabolic Process Double-strand Break Repair Cellular Process S-adenosylmethionine Metabolic Process Pyrimidine Nucleoside Metabolic Process
Tagcloud ?		11p12 14q24 6q12 9p24 abcd4 acyp1 amplifications cd109 cd274 commd9 coq6 cttn fjx1 hbld1 interscience jdp2 jpages ltbp2 myo6 otscc pdhx pinpointed ppfia1 q14 rln1 slc1a1 suppmat trim44 znf410
Tagcloud (Difference) ?		11p12 14q24 6q12 9p24 abcd4 acyp1 amplifications cd109 cd274 commd9 coq6 cttn fjx1 hbld1 interscience jdp2 jpages ltbp2 myo6 otscc pdhx pinpointed ppfia1 q14 rln1 slc1a1 suppmat trim44 znf410
Tagcloud (Intersection) ?