LSMEM1 and MAL

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LSMEM1	MAL
Gene Name		leucine-rich single-pass membrane protein 1	mal, T-cell differentiation protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Integral Component Of Membrane	Endosome Endoplasmic Reticulum Integral Component Of Plasma Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Membrane Raft
	Molecular Function		Protein Binding Lipid Binding Channel Activity Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath
	Biological Process		Membrane Raft Polarization Apoptotic Process Central Nervous System Development Cell Differentiation Myelination Apical Protein Localization Transmembrane Transport Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: APP LSMEM2 MAL	9 interactors: EDA FIBCD1 KLRC1 LDLRAD1 LSMEM1 MYD88 PTPRN SMIM3 USP7
Entrez ID		286006	4118
HPRD ID		08258	01789
Ensembl ID		ENSG00000181016	ENSG00000172005
Uniprot IDs		Q8N8F7	P21145
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Positive Regulation Of Interleukin-15 Production Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Cytotoxic T Cell Differentiation TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Regulation Of Binding Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Synaptic Growth At Neuromuscular Junction Positive Regulation Of Proteolysis Negative Regulation Of Proteolysis Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Collateral Sprouting In Absence Of Injury Membrane Raft Polarization Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Posttranscriptional Regulation Of Gene Expression Collateral Sprouting Axon Midline Choice Point Recognition Membrane Raft Localization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Axon Choice Point Recognition Regulation Of Growth Neuron Remodeling Regulation Of Proteolysis Positive Regulation Of Protein Homodimerization Activity 3'-UTR-mediated MRNA Stabilization Cell Activation Cellular Response To Bacterial Lipopeptide Positive Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Catalytic Activity Cellular Response To Lipoteichoic Acid Positive Regulation Of Interleukin-6 Biosynthetic Process Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transcription Via Serum Response Element Binding Apical Protein Localization Negative Regulation Of Protein Metabolic Process Cellular Copper Ion Homeostasis Regulation Of Protein Homodimerization Activity Apoptotic Process Membrane Raft Organization Central Nervous System Development	Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Dense Core Granule Maturation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Molecule Of Fungal Origin Trachea Gland Development Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Interleukin-23 Production Establishment Of Endothelial Intestinal Barrier Salivary Gland Cavitation Maintenance Of DNA Methylation Cellular Response To Stimulus Positive Regulation Of Interleukin-17 Production 3'-UTR-mediated MRNA Stabilization Type I Interferon Biosynthetic Process Positive Regulation Of Chemokine Biosynthetic Process Response To Peptidoglycan Toll Signaling Pathway Type I Interferon Production Cytokine-mediated Signaling Pathway Hair Follicle Placode Formation Histone Deubiquitination Positive Regulation Of NF-kappaB Import Into Nucleus Response To Stimulus Cytokine Biosynthetic Process Ectoderm Development MRNA Stabilization Negative Regulation Of Growth Of Symbiont In Host Cellular Response To Cytokine Stimulus Establishment Of Endothelial Barrier
Tagcloud ?			100ng calyculin collagen formation forming gels genestien guinea ibmx il1 il3 il6 incorporation jak1 map megakaryocyte megakaryocytes okadaic phosphatase pig proplatelet proplatelets stat stimulate thymidine tpo transduction tyk unaffected
Tagcloud (Difference) ?			100ng calyculin collagen formation forming gels genestien guinea ibmx il1 il3 il6 incorporation jak1 map megakaryocyte megakaryocytes okadaic phosphatase pig proplatelet proplatelets stat stimulate thymidine tpo transduction tyk unaffected
Tagcloud (Intersection) ?