LSMEM1 and LSMEM2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LSMEM1	LSMEM2
Gene Name		leucine-rich single-pass membrane protein 1	leucine-rich single-pass membrane protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Integral Component Of Membrane	Integral Component Of Membrane
	Molecular Function
	Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: APP LSMEM2 MAL	3 interactors: APP GIMAP5 LSMEM1
Entrez ID		286006	132228
HPRD ID		08258	08789
Ensembl ID		ENSG00000181016	ENSG00000179564
Uniprot IDs		Q8N8F7	Q8N112
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Binding Positive Regulation Of Peptidase Activity Positive Regulation Of Interleukin-15 Production Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Cytotoxic T Cell Differentiation TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Regulation Of Binding Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Synaptic Growth At Neuromuscular Junction Positive Regulation Of Proteolysis Negative Regulation Of Proteolysis Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Collateral Sprouting In Absence Of Injury Membrane Raft Polarization Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Posttranscriptional Regulation Of Gene Expression Collateral Sprouting Axon Midline Choice Point Recognition Membrane Raft Localization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Axon Choice Point Recognition Regulation Of Growth Neuron Remodeling Regulation Of Proteolysis Positive Regulation Of Protein Homodimerization Activity 3'-UTR-mediated MRNA Stabilization Cell Activation Cellular Response To Bacterial Lipopeptide Positive Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Catalytic Activity Cellular Response To Lipoteichoic Acid Positive Regulation Of Interleukin-6 Biosynthetic Process Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transcription Via Serum Response Element Binding Apical Protein Localization Negative Regulation Of Protein Metabolic Process Cellular Copper Ion Homeostasis Regulation Of Protein Homodimerization Activity Apoptotic Process Membrane Raft Organization Central Nervous System Development	Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth RNA 3'-end Processing Cholesterol Metabolic Process Adult Locomotory Behavior Positive Regulation Of Mitotic Cell Cycle Regulation Of Receptor Activity Cell Recognition
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