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RTP5 and DOCK8
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
RTP5
DOCK8
Gene Name
receptor (chemosensory) transporter protein 5 (putative)
dedicator of cytokinesis 8
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Integral Component Of Membrane
Cytosol
Membrane
Cell Leading Edge
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Biological Process
Immunological Synapse Formation
Small GTPase Mediated Signal Transduction
Blood Coagulation
Dendritic Cell Migration
Positive Regulation Of GTPase Activity
Memory T Cell Proliferation
Negative Regulation Of T Cell Apoptotic Process
Pathways
Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Mean platelet volume (
22139419
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
27 interactors:
ACTN2
BEND5
CALCOCO2
CARD9
DOCK8
GOLGA2
HNRNPK
KRT40
LZTS2
MDFI
MIPOL1
MTUS2
PDE4DIP
PNMA1
PNMA2
PSMA3
PSMA6
PSTPIP1
RBPMS
RINT1
ROPN1
SP100
SPDL1
SPERT
TRAF1
TRIM23
TSGA10
25 interactors:
BYSL
CARHSP1
CDC42
CHMP2A
DGCR6
EXOSC5
FAM124A
FAM161A
FANCL
FBXL12
HBZ
KRT40
LRCH1
LRCH3
MED30
MEOX2
MRPL38
MTG1
RAC1
RHOJ
RHOQ
RTP5
SMAD2
ZFC3H1
ZNF581
Entrez ID
285093
81704
HPRD ID
08159
10920
Ensembl ID
ENSG00000107099
Uniprot IDs
Q14D33
E2J6M5
E2J6M6
Q8NF50
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Apoptotic Process
Regulation Of Cell Death
Viral Process
Negative Regulation Of Wnt Signaling Pathway
Regulation Of Signal Transduction
DNA Damage Response, Signal Transduction By P53 Class Mediator
Signal Transduction In Response To DNA Damage
Negative Regulation Of Binding
Regulation Of Signaling
Regulation Of Wnt Signaling Pathway
Signal Transduction By P53 Class Mediator
Regulation Of Cellular Localization
Negative Regulation Of Canonical Wnt Signaling Pathway
Response To Stress
Immune System Process
Mitotic Cell Cycle
Regulation Of Protein Localization
Regulation Of Intracellular Transport
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Regulation Of Protein Localization To Nucleus
Intracellular Receptor Signaling Pathway
Negative Regulation Of DNA Binding
Intracellular Signal Transduction
Cell Cycle
Regulation Of Nucleocytoplasmic Transport
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Signaling
Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint
Memory T Cell Proliferation
Cell Cycle Checkpoint
Cell Communication
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Positive Regulation Of Metabolic Process
Signal Transduction Involved In Cell Cycle Checkpoint
Regulation Of Binding
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Intracellular Protein Transport
Negative Regulation Of Ubiquitin-protein Transferase Activity
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Fas Signaling Pathway
Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Transferase Activity
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Regulation Of Cell Morphogenesis
Regulation Of Cell Projection Assembly
Positive Regulation Of Phosphatidylinositol 3-kinase Activity
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Cell Morphogenesis Involved In Differentiation
Regulation Of Substrate Adhesion-dependent Cell Spreading
Anatomical Structure Morphogenesis
Posttranscriptional Regulation Of Gene Expression
Ribosome Biogenesis
Regulation Of Cellular Component Organization
Regulation Of Cytoskeleton Organization
Regulation Of Organelle Organization
Regulation Of Filopodium Assembly
Regulation Of Phosphatidylinositol 3-kinase Activity
Negative Regulation Of Centriole Elongation
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Lipid Kinase Activity
Anatomical Structure Formation Involved In Morphogenesis
Actin Cytoskeleton Organization
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of DNA Replication
Small GTPase Mediated Signal Transduction
Positive Regulation Of Cell Projection Organization
Cell Projection Assembly
Embryonic Olfactory Bulb Interneuron Precursor Migration
Negative Regulation Of Interleukin-23 Production
Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Positive Regulation Of Hair Follicle Cell Proliferation
Actin Filament-based Process
T Cell Costimulation
Positive Regulation Of Cellular Component Biogenesis
Ribonucleoprotein Complex Biogenesis
Embryonic Pattern Specification
Regulation Of Protein Complex Assembly
Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Engulfment Of Apoptotic Cell
Submandibular Salivary Gland Formation
Actin Filament Branching
Zygotic Specification Of Dorsal/ventral Axis
Regulation Of Small GTPase Mediated Signal Transduction
Anatomical Structure Development
Ephrin Receptor Signaling Pathway
Intracellular Signal Transduction
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Mast Cell Chemotaxis
Regulation Of Hair Follicle Cell Proliferation
Positive Regulation Of Synapse Structural Plasticity
Palate Development
Positive Regulation Of Cell-substrate Adhesion
Regulation Of Mitotic Nuclear Division
Tagcloud
?
akr1c4
anomalies
apparently
array
balanced
bases
cdon
cgh
chrna7
confirming
dd
diagnoses
gata3
id
indistinguishable
inherited
intellectual
karyotype
karyotyping
mb
mca
nr2f2
overlooked
prenatal
pws
rearrangements
spanning
tier
tp63
Tagcloud (Difference)
?
akr1c4
anomalies
apparently
array
balanced
bases
cdon
cgh
chrna7
confirming
dd
diagnoses
gata3
id
indistinguishable
inherited
intellectual
karyotype
karyotyping
mb
mca
nr2f2
overlooked
prenatal
pws
rearrangements
spanning
tier
tp63
Tagcloud (Intersection)
?