KANSL1 and HOOK2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KANSL1	HOOK2
Gene Name		KAT8 regulatory NSL complex subunit 1	hook microtubule-tethering protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Condensed Chromosome Kinetochore Nucleus Nucleoplasm MLL1 Complex	Centrosome Microtubule HOPS Complex FHF Complex
	Molecular Function	Protein Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific)	Protein Binding Identical Protein Binding
	Biological Process	Chromatin Organization Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation	Endocytosis Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Early Endosome To Late Endosome Transport
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: CALCOCO2 CCDC136 CCDC85B CDC5L CDR2 CEP70 DISC1 DTNBP1 EXOC1 FSD2 GOLGA2 HOOK2 KAT8 KDM1A KIFC3 KRT15 MAGEA12 NECAB2 NINL NUP62 NUTM1 PLEKHA5 PNMA1 PSME3 SMAD3 SPAG5 TFIP11 TP53 TRAF2 TRAF4 TRIM27 USHBP1	31 interactors: ABLIM1 AKTIP ANKRD11 ANKRD36BP1 AP1M1 APEX2 CCDC33 CWF19L2 DUSP13 EPS8 FAM107A HOOK1 HOOK3 IQCE ITSN2 KANSL1 KAT7 KIAA0408 MCM10 PSMF1 RALBP1 RIBC2 SUV39H1 USP2 UTP14A UTP14C VPS16 VPS41 ZC2HC1C ZNF250 ZNF638
Entrez ID		284058	29911
HPRD ID		11254	09698
Ensembl ID		ENSG00000120071	ENSG00000095066
Uniprot IDs		I3L4J3 Q7Z3B3	Q96ED9
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Regulation Of Binding Cell Cycle Process Mitotic Cell Cycle Regulation Of Protein Binding Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Protein Homodimerization Activity Mitotic Cell Cycle Process Regulation Of Apoptotic Process Regulation Of Cellular Protein Metabolic Process Signal Transduction In Response To DNA Damage Regulation Of Cell Death Regulation Of Protein Homodimerization Activity Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Neural Precursor Cell Proliferation Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Stem Cell Proliferation Positive Regulation Of Proteolysis Viral Process Positive Regulation Of Signal Transduction Immune System Process Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Process Positive Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of Programmed Cell Death Positive Regulation Of Endopeptidase Activity Negative Regulation Of Cell Death Positive Regulation Of Peptidase Activity NIK/NF-kappaB Signaling DNA Damage Checkpoint Protein K63-linked Ubiquitination Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of Cell Growth Positive Regulation Of Wnt Signaling Pathway Regulation Of Cellular Localization Protein Trimerization Cell Death Death Regulation Of Protein Phosphorylation Protein Polyubiquitination Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Protein Metabolic Process Programmed Necrotic Cell Death Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Necrotic Cell Death Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of RNA Biosynthetic Process	Early Endosome To Late Endosome Transport Vacuolar Transport Endosomal Transport Vacuole Organization Endosome To Lysosome Transport Endosome Organization Lysosomal Transport Regulation Of SNARE Complex Assembly Lysosome Organization Cell Cycle Histone H4-K5 Acetylation Histone H4-K8 Acetylation Organelle Organization RRNA Processing RRNA Metabolic Process Maturation Of SSU-rRNA Cytoplasmic Transport Regulation Of Vesicle Fusion Ribosomal Small Subunit Biogenesis Ribosome Biogenesis Regulation Of Vacuole Fusion, Non-autophagic Vacuole Fusion, Non-autophagic Histone H4 Acetylation Peptidyl-lysine Modification Viral Process Protein Transport Actin Polymerization-dependent Cell Motility Vesicle-mediated Transport Establishment Of Protein Localization
Tagcloud ?		acquisition amkl clone cohesin constitutive ctcf ds evolve evolves existing exome gata1 jak limiting lnk megakaryoblastic mostly mpl mutational myelopoiesis perinatal profiling remission resembling sh2b3 spontaneous tam trisomy whole	accumulated approaches basic benign demonstrates encoding hmga hmga2 initiating leiomyoma leiomyomas limits mesenchymal mobility myometrial opens origin possibilities putative rearrangements side sp stem toward transformation truncated understand uterine work
Tagcloud (Difference) ?		acquisition amkl clone cohesin constitutive ctcf ds evolve evolves existing exome gata1 jak limiting lnk megakaryoblastic mostly mpl mutational myelopoiesis perinatal profiling remission resembling sh2b3 spontaneous tam trisomy whole	accumulated approaches basic benign demonstrates encoding hmga hmga2 initiating leiomyoma leiomyomas limits mesenchymal mobility myometrial opens origin possibilities putative rearrangements side sp stem toward transformation truncated understand uterine work
Tagcloud (Intersection) ?