KANSL1

Gene Name		KAT8 regulatory NSL complex subunit 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Condensed Chromosome Kinetochore Nucleus Nucleoplasm MLL1 Complex
	Molecular Function	Protein Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific)
	Biological Process	Chromatin Organization Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-protein Interactions		32 interactors: CALCOCO2 CCDC136 CCDC85B CDC5L CDR2 CEP70 DISC1 DTNBP1 EXOC1 FSD2 GOLGA2 HOOK2 KAT8 KDM1A KIFC3 KRT15 MAGEA12 NECAB2 NINL NUP62 NUTM1 PLEKHA5 PNMA1 PSME3 SMAD3 SPAG5 TFIP11 TP53 TRAF2 TRAF4 TRIM27 USHBP1
Entrez ID		284058
HPRD ID		11254
Ensembl ID		ENSG00000120071
Uniprot IDs		I3L4J3 Q7Z3B3
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cell Cycle Regulation Of Binding Cell Cycle Process Mitotic Cell Cycle Regulation Of Protein Binding Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Protein Homodimerization Activity Mitotic Cell Cycle Process Regulation Of Apoptotic Process Regulation Of Cellular Protein Metabolic Process Signal Transduction In Response To DNA Damage Regulation Of Cell Death Regulation Of Protein Homodimerization Activity Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Neural Precursor Cell Proliferation Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Stem Cell Proliferation Positive Regulation Of Proteolysis Viral Process Positive Regulation Of Signal Transduction Immune System Process Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Process Positive Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of Programmed Cell Death Positive Regulation Of Endopeptidase Activity Negative Regulation Of Cell Death Positive Regulation Of Peptidase Activity NIK/NF-kappaB Signaling DNA Damage Checkpoint Protein K63-linked Ubiquitination Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of Cell Growth Positive Regulation Of Wnt Signaling Pathway Regulation Of Cellular Localization Protein Trimerization Cell Death Death Regulation Of Protein Phosphorylation Protein Polyubiquitination Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Protein Metabolic Process Programmed Necrotic Cell Death Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Necrotic Cell Death Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of RNA Biosynthetic Process
Tagcloud ?		acquisition amkl clone cohesin constitutive ctcf ds evolve evolves existing exome gata1 jak limiting lnk megakaryoblastic mostly mpl mutational myelopoiesis perinatal profiling remission resembling sh2b3 spontaneous tam trisomy whole