KANSL1 and NUTM1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KANSL1	NUTM1
Description		KAT8 regulatory NSL complex subunit 1	NUT midline carcinoma family member 1
Image
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Chromosome, Centromeric Region Kinetochore Spindle Pole Nucleus Nucleoplasm Chromosome Cytoplasm Mitochondrion Cytoskeleton Microtubule NSL Complex MLL1 Complex H4 Histone Acetyltransferase Complex	Nucleus Cytoplasm
	Molecular Function	Protein Binding Histone Acetyltransferase Binding	Protein Binding
	Biological Process	Chromatin Organization Positive Regulation Of DNA-templated Transcription Regulation Of Mitochondrial Transcription
Pathways		HATs acetylate histones Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		A body shape index ( 34021172) Alcohol use disorder (total score) ( 30336701) Alzheimer's disease in APOE e4- carriers ( 25778476) Automobile speeding propensity ( 30643258) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683) Chronotype ( 30696823) Cognitive ability ( 29186694) Cognitive function ( 28093568) Eosinophil count ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) General factor of neuroticism ( 30867560) Hand grip strength ( 29313844) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Household income ( 31844048) Idiopathic pulmonary fibrosis ( 24429156) Language functional connectivity ( 34929384) Left–right brain asymmetry ( 33723403) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lung function (FEV1) ( 28166213) Lung function (FVC) ( 28166213) Lung function (low FEV1 vs high FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Lymphocyte percentage of white cells ( 27863252) Macular thickness ( 30535121) Male-pattern baldness ( 28196072 27182965) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular volume ( 29403010 27863252) Mean reticulocyte volume ( 32888494) Monocyte percentage of white cells ( 32888494) Neuroticism ( 29255261) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 27863252 32888494) Oily fish consumption ( 32066663) Osteoarthrosis (time to event) ( 32589924) Parkinson's disease ( 28892059 32201043 31660654) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Plateletcrit ( 32888494) Pork consumption ( 32066663) Pulse pressure ( 27841878) Reaction time ( 29844566) Red blood cell count ( 29403010) Red cell distribution width ( 28957414 32888494) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252 32888494) Risk-taking tendency (4-domain principal component model) ( 30643258) Sum eosinophil basophil counts ( 27863252) Systolic blood pressure ( 27841878) Ventral diencephalon volume ( 31530798) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White matter integrity (mean diffusivity) ( 32358547)
Interacting Genes		33 interacting genes: BAZ1B CALCOCO2 CCDC136 CCDC85B CDC5L CDR2 CEP70 DISC1 DTNBP1 EXOC1 FSD2 GOLGA2 HOOK2 HSPB1 KDM1A KIFC3 KRT15 MAGEA12 MDFI NECAB2 NINL NUP62 NUTM1 PLEKHA5 PNMA1 PSME3 SMAD3 SPAG5 TFIP11 TRAF2 TRAF4 TRIM27 USHBP1	54 interacting genes: ALOX5 AQP1 ARHGEF6 AXIN1 CATSPERT CCDC116 CCDC185 CCHCR1 CDC20B CDK18 CHCHD3 ENKD1 FAM161A GADD45GIP1 GPANK1 HSPBAP1 IFIT2 KANK2 KANSL1 KPNA2 LHX8 LMO1 LMO2 LMO3 LRRC8E MBD3 METTL17 MORN4 MTCL2 NEBL OSTF1 P4HA3 PLEKHF2 PRKAA2 PRKAB2 PRPF18 PSME4 RCOR3 RIC8A SAMD4A SAMD4B SCNM1 SH2D1B SH2D4A SMARCD1 TBC1D21 TEAD4 TLE5 TP53BP2 TSGA10IP TTC23 TXN2 ZMYND10 ZNF277
Entrez ID		284058	256646
HPRD ID		11254	10606
Ensembl ID		ENSG00000120071	ENSG00000184507
Uniprot IDs		A0A0G2JNB1 A0A0G2JNT7 A0A1W2PRB5 A0A3B3IT55 A0A9S7M8F4 Q7Z3B3	A0AAG2UVG0 A0AAG2UVR5 A0AAG2UXE6 Q86Y26
PDB IDs		4CY1 4CY2	7XEZ 7XFG
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Cytoskeleton Cytoplasm Microtubule-based Process Centrosome Regulation Of Cellular Component Organization Microtubule Organelle Organization Thioesterase Binding Protein Binding Positive Regulation Of Cellular Component Organization	Protein Binding
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