SLCO3A1 and SLC9A3R2

Number of citations of the paper that reports this interaction (PMID 15553237)
5

Data Source:
HPRD (two hybrid)

		SLCO3A1	SLC9A3R2
Gene Name		solute carrier organic anion transporter family, member 3A1	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleus Cytoplasm Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Transporter Activity	Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding
	Biological Process	Sodium-independent Organic Anion Transport Transmembrane Transport	Protein Complex Assembly Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) DNA methylation (variation) ( 23725790) Inattentive symptoms ( 18821565) Obesity-related traits ( 23251661) Response to iloperidone treatment (QT prolongation) ( 18521091)
Protein-Protein Interactions		3 interactors: PDZD3 SLC9A3R1 SLC9A3R2	35 interactors: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDPK1 PDZK1 PIK3CA PLCB3 PODXL PRKACA PTEN PTH1R RDX SGK1 SGK3 SIAH1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A WWTR1
Entrez ID		28232	9351
HPRD ID		07502	05946
Ensembl ID		ENSG00000176463	ENSG00000065054
Uniprot IDs		Q9UIG8	Q15599
PDB IDs			2D11 2HE4 2OCS
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of CGMP Biosynthetic Process Renal Phosphate Ion Absorption Negative Regulation Of Guanylate Cyclase Activity Glutathione Transport Negative Regulation Of Sodium:proton Antiporter Activity Renal Sodium Ion Transport Cellular Phosphate Ion Homeostasis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Intracellular Signal Transduction Phospholipase C-activating Dopamine Receptor Signaling Pathway Bile Acid Secretion CGMP-mediated Signaling Receptor Guanylyl Cyclase Signaling Pathway Oligopeptide Transport Negative Regulation Of Sodium Ion Transport Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Renal Absorption Regulation Of Proton Transport Phosphate Ion Homeostasis Microvillus Assembly Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Microvillus Organization Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of CGMP Biosynthetic Process Negative Regulation Of Lyase Activity Regulation Of Excretion Regulation Of Sodium Ion Transmembrane Transporter Activity Cyclic-nucleotide-mediated Signaling Bile Acid And Bile Salt Transport Regulation Of CGMP Metabolic Process Dopamine Receptor Signaling Pathway Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Nucleotide Metabolic Process Negative Regulation Of Transporter Activity Water Transport Protein Complex Assembly Anion Homeostasis Fluid Transport Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Signal Transduction Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Transmembrane Transport Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Signaling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Regulation Of Protein Kinase Activity Ion Homeostasis Transmembrane Transport Regulation Of Kinase Activity Regulation Of Ion Transport Positive Regulation Of Ion Transport Regulation Of Protein Phosphorylation Homeostatic Process Positive Regulation Of Transport Ion Transport Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Phosphorylation Ion Transmembrane Transport Cellular Cation Homeostasis Organic Anion Transport Cellular Ion Homeostasis Cytosolic Calcium Ion Homeostasis Chemical Homeostasis Positive Regulation Of Protein Kinase Activity Blood Circulation Positive Regulation Of Cellular Protein Metabolic Process Anion Transport Platelet Activation Positive Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Transport Positive Regulation Of Protein Phosphorylation Sodium-independent Organic Anion Transport Carnitine Transport Cellular Chemical Homeostasis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Body Fluid Levels Monocarboxylic Acid Transport Sperm Capacitation Anion Transmembrane Transport Regulation Of Cellular Component Organization Sodium Ion Transport Inorganic Anion Transport Regulation Of Cellular Protein Metabolic Process Response To Organonitrogen Compound Regulation Of Ion Transmembrane Transport Blood Coagulation Hemostasis Activation Of Protein Kinase Activity Positive Regulation Of Phosphorylation Quaternary Ammonium Group Transport Positive Regulation Of Cytosolic Calcium Ion Concentration
Tagcloud ?		2b1 abcb1 abcc1 abcc2 abcc3 abcc4 abcc5 abcg2 antiretroviral antiretrovirals bcrp darunavir fold gp ls180 mdr1 mrp1 mrp2 mrp3 mrp4 mrp5 pharmacokinetics sanctuary saquinavir suboptimal transporters transporting
Tagcloud (Difference) ?		2b1 abcb1 abcc1 abcc2 abcc3 abcc4 abcc5 abcg2 antiretroviral antiretrovirals bcrp darunavir fold gp ls180 mdr1 mrp1 mrp2 mrp3 mrp4 mrp5 pharmacokinetics sanctuary saquinavir suboptimal transporters transporting
Tagcloud (Intersection) ?