SLCO3A1

Gene Name		solute carrier organic anion transporter family, member 3A1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Transporter Activity
	Biological Process	Sodium-independent Organic Anion Transport Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) DNA methylation (variation) ( 23725790) Inattentive symptoms ( 18821565) Obesity-related traits ( 23251661) Response to iloperidone treatment (QT prolongation) ( 18521091)
Protein-protein Interactions		3 interactors: PDZD3 SLC9A3R1 SLC9A3R2
Entrez ID		28232
HPRD ID		07502
Ensembl ID		ENSG00000176463
Uniprot IDs		Q9UIG8
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of CGMP Biosynthetic Process Renal Phosphate Ion Absorption Negative Regulation Of Guanylate Cyclase Activity Glutathione Transport Negative Regulation Of Sodium:proton Antiporter Activity Renal Sodium Ion Transport Cellular Phosphate Ion Homeostasis Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Intracellular Signal Transduction Phospholipase C-activating Dopamine Receptor Signaling Pathway Bile Acid Secretion CGMP-mediated Signaling Receptor Guanylyl Cyclase Signaling Pathway Oligopeptide Transport Negative Regulation Of Sodium Ion Transport Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Renal Absorption Regulation Of Proton Transport Phosphate Ion Homeostasis Microvillus Assembly Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Microvillus Organization Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of CGMP Biosynthetic Process Negative Regulation Of Lyase Activity Regulation Of Excretion Regulation Of Sodium Ion Transmembrane Transporter Activity Cyclic-nucleotide-mediated Signaling Bile Acid And Bile Salt Transport Regulation Of CGMP Metabolic Process Dopamine Receptor Signaling Pathway Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Nucleotide Metabolic Process Negative Regulation Of Transporter Activity Water Transport Protein Complex Assembly Anion Homeostasis Fluid Transport Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Signal Transduction Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Transmembrane Transport Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Signaling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Tagcloud ?		2b1 abcb1 abcc1 abcc2 abcc3 abcc4 abcc5 abcg2 antiretroviral antiretrovirals bcrp darunavir fold gp ls180 mdr1 mrp1 mrp2 mrp3 mrp4 mrp5 pharmacokinetics sanctuary saquinavir suboptimal transporters transporting