SLCO3A1

Description		solute carrier organic anion transporter family member 3A1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding Organic Anion Transmembrane Transporter Activity Prostaglandin Transmembrane Transporter Activity Sodium-independent Organic Anion Transmembrane Transporter Activity
	Biological Process	Monoatomic Ion Transport Prostaglandin Transport Positive Regulation Of Canonical NF-kappaB Signal Transduction Sodium-independent Organic Anion Transport Positive Regulation Of MAPK Cascade Transmembrane Transport Transport Across Blood-brain Barrier
Pathways
Drugs
Diseases
GWAS		Acute lymphoblastic leukemia (childhood) ( 22076464) Adult body size ( 32376654) Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Diastolic blood pressure ( 30224653) DNA methylation (variation) ( 23725790) Estimated glomerular filtration rate reduction (30%) ( 30955190) Gastroesophageal reflux disease ( 27485664) Inattentive symptoms ( 18821565) Neuritic plaque ( 25188341) Obesity-related traits ( 23251661) Orofacial cleft x maternal periconceptional alcohol use interaction (1df) ( 33937227) Post bronchodilator FEV1/FVC ratio ( 26634245) Primary sclerosing cholangitis ( 27992413) Refractive error ( 32231278) Response to iloperidone treatment (QT prolongation) ( 18521091) Smoking initiation ( 24665060)
Novel Interacting Genes		1 novel interacting genes: ACAN
Interacting Genes		7 interacting genes: AQP6 ARLN GOLM1 NHERF1 NHERF2 NHERF4 TRARG1
Entrez ID		28232
HPRD ID		07502
Ensembl ID		ENSG00000176463
Uniprot IDs		Q9UIG8
PDB IDs
Enriched GO Terms of Interacting Partners?		Type 3 Metabotropic Glutamate Receptor Binding Protein-membrane Adaptor Activity Type 2 Metabotropic Glutamate Receptor Binding Protein Localization To Plasma Membrane Protein Localization To Cell Periphery Protein Localization To Membrane Water Transport Localization Within Membrane Fluid Transport Endomembrane System Phosphatase Binding Nitrate Transmembrane Transporter Activity Renal Phosphate Ion Absorption Guanylate Cyclase Inhibitor Activity Apical Plasma Membrane Signaling Receptor Binding Apical Part Of Cell PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Regulation Of Renal Phosphate Excretion Dopamine Receptor Binding Beta-catenin Binding Renal System Process Carbon Dioxide Transmembrane Transporter Activity Cytoplasmic Vesicle Membrane Carbon Dioxide Transmembrane Transport Cellular Localization Molecular Adaptor Activity Maintenance Of Epithelial Cell Apical/basal Polarity Bile Acid Secretion Microvillus Assembly Channel Activator Activity Gamma-aminobutyric Acid Transmembrane Transporter Activity Beta-2 Adrenergic Receptor Binding Chloride Channel Regulator Activity Gamma-aminobutyric Acid Import Growth Factor Receptor Binding Negative Regulation Of CGMP-mediated Signaling Glucose Import In Response To Insulin Stimulus Monoatomic Anion Channel Activity Renal Water Transport Microvillus Organization Establishment Of Golgi Localization Phospholipase C-activating Dopamine Receptor Signaling Pathway Ammonium Channel Activity Intracellular Phosphate Ion Homeostasis Extracellular Matrix Structural Constituent Conferring Compression Resistance Perineuronal Net Ammonium Transmembrane Transport Water Channel Activity
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