GOLGB1 and SREBF2

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		GOLGB1	SREBF2
Gene Name		golgin B1	sterol regulatory element binding transcription factor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi Stack Cis-Golgi Network Membrane Integral Component Of Membrane	Golgi Membrane Nucleus Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane SREBP-SCAP-Insig Complex
	Molecular Function	Protein Binding Poly(A) RNA Binding	C-8 Sterol Isomerase Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Protein C-terminus Binding Protein Dimerization Activity E-box Binding
	Biological Process	Golgi Organization	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Lipid Metabolic Process Cholesterol Metabolic Process Positive Regulation Of Cholesterol Storage Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Low-density Lipoprotein Particle Cellular Response To Laminar Fluid Shear Stress Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cholesterol Efflux Regulation Of Cholesterol Homeostasis
Pathways			Regulation of cholesterol biosynthesis by SREBP (SREBF) PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Transcriptional regulation of white adipocyte differentiation Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: ACBD3 BRMS1 CAV2 ITSN2 KIAA0368 KIAA1377 MAPK7 NDUFA1 PFN2 SKIL SLC2A3 SREBF2 UBE2I USO1 VTI1B	48 interactors: ABLIM1 ABLIM2 ARHGEF1 ARRB1 ATF7IP ATXN1 CASP3 CASP8AP2 COPS5 CREB1 CREBBP EGR1 EP300 FHL3 GOLGB1 HDAC3 HNF4A HSPA5 INSIG1 INSIG2 ITGB4 KLF13 KPNB1 LZTR1 MAPK1 MAPK3 MRPS6 NAE1 NFYA NFYC OS9 PIAS1 PIAS2 PIAS3 PSMD4 RAB11B SCAP SLC4A4 SMAD3 SP1 SPTBN1 SREBF1 SUMO1 TTC1 UBE2I ZDHHC17 ZMYM2 ZYX
Entrez ID		2804	6721
HPRD ID		03933	02726
Ensembl ID		ENSG00000173230	ENSG00000198911
Uniprot IDs		F1T0J2 Q14789	Q12772
PDB IDs			1UKL
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Cellular Response To Laminar Fluid Shear Stress Vesicle Fusion With Golgi Apparatus Organelle Fusion Vesicle Docking Membrane Docking Cellular Response To Fluid Shear Stress Response To Laminar Fluid Shear Stress Membrane Fusion Response To Fluid Shear Stress Vesicle Organization Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Golgi Vesicle Docking Negative Regulation Of CAMP Catabolic Process Organelle Organization ER To Golgi Vesicle-mediated Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Anoikis Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Metabolic Process Negative Regulation Of Cholesterol Efflux Skeletal Muscle Tissue Development Negative Regulation Of Ruffle Assembly Skeletal Muscle Organ Development Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of NFAT Protein Import Into Nucleus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Golgi To Vacuole Transport Negative Regulation Of Heterotypic Cell-cell Adhesion Caveola Assembly Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Response To Transforming Growth Factor Beta Positive Regulation Of Signal Transduction Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Cholesterol Transport Membrane Raft Assembly	Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Signaling Viral Process RNA Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Signal Transduction Signaling Protein Sumoylation Cell Communication Negative Regulation Of Biosynthetic Process Response To Organic Substance Regulation Of Metabolic Process Biosynthetic Process Cellular Response To Organic Substance Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Signal Transduction Cellular Response To Stress Cell Surface Receptor Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Response To Stimulus Positive Regulation Of Protein Metabolic Process Cellular Response To Stimulus Rhythmic Process Nitrogen Compound Metabolic Process Cellular Response To Growth Factor Stimulus Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud ?			33a adipogenesis adipose beef bovine british cattle clustered conservation conserved continental coordinated coordinately crossbred determinant ebpalpha ep300 exonic intergenic intronic location micrornas mirna mirnas mirtron profiled qrt steers subcutaneous
Tagcloud (Difference) ?			33a adipogenesis adipose beef bovine british cattle clustered conservation conserved continental coordinated coordinately crossbred determinant ebpalpha ep300 exonic intergenic intronic location micrornas mirna mirnas mirtron profiled qrt steers subcutaneous
Tagcloud (Intersection) ?