GOLGB1 and SLC2A3

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		GOLGB1	SLC2A3
Name		golgin B1	solute carrier family 2 member 3
Structure		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi Stack Cis-Golgi Network Cytosol Membrane	Plasma Membrane Membrane Aggresome Secretory Granule Membrane Specific Granule Membrane Cell Projection Perikaryon Extracellular Exosome Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	RNA Binding Protein Binding Sequence-specific DNA Binding	Fructose Transmembrane Transporter Activity Galactose Transmembrane Transporter Activity Protein Binding D-glucose Binding Transmembrane Transporter Activity Dehydroascorbic Acid Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity
	Biological Process	Regulation Of DNA-templated Transcription Golgi Organization Protein Localization To Pericentriolar Material	Carbohydrate Metabolic Process Fructose Transmembrane Transport Galactose Transmembrane Transport L-ascorbic Acid Metabolic Process D-glucose Import Transmembrane Transport Dehydroascorbic Acid Transport D-glucose Import Across Plasma Membrane Transport Across Blood-brain Barrier D-glucose Transmembrane Transport
Pathways		Golgi Associated Vesicle Biogenesis COPI-mediated anterograde transport Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins	Cellular hexose transport Vitamin C (ascorbate) metabolism Neutrophil degranulation MECP2 regulates neuronal receptors and channels
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Mean reticulocyte volume ( 32888494 )	Age-related cognitive decline (language) (slope of z-scores) ( 30954325 ) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971 )
Novel Interactors		2 novel interactors: INTS5 POGK	None recorded
Interacting Genes		19 interacting genes: ACBD3 ADRB2 BRMS1 CAV2 CEP126 ECPAS ITSN2 MAPK7 NDUFA1 NOD2 PFN2 RNF10 SKIL SLC2A3 SREBF2 UBE2I USO1 USP7 VTI1B	6 interacting genes: CREB3 CREB3L1 GOLGB1 MTNR1A MTNR1B SNTA1
Entrez ID		2804	6515
HPRD ID		03933	00686
Ensembl ID		ENSG00000173230	ENSG00000059804
Uniprot IDs		A0A8J9C4H3 E7EU81 Q14789	P11169
PDB IDs		Not available	4ZW9 4ZWB 4ZWC 5C65 7CRZ 7SPS 7SPT
GO Terms Enriched among Interactors		PML Body Vesicle Docking ER To Golgi Transport Vesicle Membrane Vesicle Fusion With Golgi Apparatus Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Cellular Response To Laminar Fluid Shear Stress Organelle Membrane Fusion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Laminar Fluid Shear Stress Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Signal Transduction Temperature Homeostasis Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of RNA Metabolic Process Positive Regulation Of Autophagy Receptor-mediated Endocytosis Regulation Of Autophagy Positive Regulation Of Mini Excitatory Postsynaptic Potential Golgi Apparatus Cytoplasm Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Organelle Fusion Membrane Fusion Cellular Response To Fluid Shear Stress Response To Fluid Shear Stress SUMO Conjugating Enzyme Activity Golgi Vesicle Docking Detection Of Muramyl Dipeptide Muramyl Dipeptide Binding Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Mitophagy	Melatonin Receptor Activity Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Negative Regulation Of Response To Endoplasmic Reticulum Stress Endoplasmic Reticulum Unfolded Protein Response Response To Unfolded Protein Positive Regulation Of Deacetylase Activity Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Localization To Pericentriolar Material Extracellular Matrix Constituent Secretion Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Syntrophin Complex CCR1 Chemokine Receptor Binding Release From Viral Latency Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Process Positive Regulation Of Transmission Of Nerve Impulse Negative Regulation Of Programmed Cell Death Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Blood Circulation CAMP Response Element Binding Protein Binding Membrane Nitric-oxide Synthase Binding CAMP Response Element Binding Negative Regulation Of Vasoconstriction Regulation Of CGMP-mediated Signaling Hormone Binding Regulation Of Transmission Of Nerve Impulse Negative Regulation Of Cytosolic Calcium Ion Concentration Dystrophin-associated Glycoprotein Complex Ventricular Cardiac Muscle Cell Action Potential Regulation Of Metal Ion Transport Induction Of Positive Chemotaxis Protein Localization To Centrosome G Protein-coupled Receptor Activity Mating Behavior Negative Regulation Of Signal Transduction Positive Regulation Of Circadian Rhythm Negative Regulation Of Nervous System Process Regulation Of Membrane Potential Regulation Of Circadian Sleep/wake Cycle, Sleep