GOLGB1 and NDUFA1

Number of citations: 0 (PubMedID 16169070)
Data Source: HPRD (two hybrid)

		GOLGB1	NDUFA1
Name		golgin B1	NADH:ubiquinone oxidoreductase subunit A1
Structure		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi Stack Cis-Golgi Network Cytosol Membrane	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane Respiratory Chain Complex I
	Molecular Function	RNA Binding Protein Binding Sequence-specific DNA Binding	NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Regulation Of DNA-templated Transcription Golgi Organization Protein Localization To Pericentriolar Material	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		Golgi Associated Vesicle Biogenesis COPI-mediated anterograde transport Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins	Respiratory electron transport Complex I biogenesis
Drugs		None	NADH
Diseases		None	Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514 ) Mean reticulocyte volume ( 32888494 )	No GWAS studies recorded
Novel Interactors		2 novel interactors: INTS5 POGK	None recorded
Interacting Genes		19 interacting genes: ACBD3 ADRB2 BRMS1 CAV2 CEP126 ECPAS ITSN2 MAPK7 NDUFA1 NOD2 PFN2 RNF10 SKIL SLC2A3 SREBF2 UBE2I USO1 USP7 VTI1B	3 interacting genes: GOLGB1 TRIM55 TRIM63
Entrez ID		2804	4694
HPRD ID		03933	02093
Ensembl ID		ENSG00000173230	ENSG00000125356
Uniprot IDs		A0A8J9C4H3 E7EU81 Q14789	O15239 Q6IBB5
PDB IDs		Not available	5XTC 5XTD 5XTH 5XTI
GO Terms Enriched among Interactors		PML Body Vesicle Docking ER To Golgi Transport Vesicle Membrane Vesicle Fusion With Golgi Apparatus Organelle Localization By Membrane Tethering Membrane Docking Vesicle Fusion Cellular Response To Laminar Fluid Shear Stress Organelle Membrane Fusion Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Laminar Fluid Shear Stress Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Signal Transduction Temperature Homeostasis Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Regulation Of RNA Metabolic Process Positive Regulation Of Autophagy Receptor-mediated Endocytosis Regulation Of Autophagy Positive Regulation Of Mini Excitatory Postsynaptic Potential Golgi Apparatus Cytoplasm Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Organelle Fusion Membrane Fusion Cellular Response To Fluid Shear Stress Response To Fluid Shear Stress SUMO Conjugating Enzyme Activity Golgi Vesicle Docking Detection Of Muramyl Dipeptide Muramyl Dipeptide Binding Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Mitophagy	Protein Localization To Pericentriolar Material Ubiquitin Protein Ligase Activity Microtubule Diapedesis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Muscle Atrophy Protein Localization To Centrosome Leukocyte Migration Involved In Inflammatory Response Macrophage Migration Protein Ubiquitination Innate Immune Response Protein Modification By Small Protein Conjugation M Band Negative Regulation Of Glycolytic Process Titin Binding Contractile Muscle Fiber Negative Regulation Of ATP Metabolic Process Defense Response To Other Organism Defense Response To Symbiont Golgi Stack Post-translational Protein Modification Response To Electrical Stimulus Negative Regulation Of Muscle Hypertrophy Negative Regulation Of Cardiac Muscle Hypertrophy Cis-Golgi Network Protein Localization To Cytoskeleton Regulation Of Glycolytic Process Canonical NF-kappaB Signal Transduction Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Carbohydrate Catabolic Process Response To Other Organism Protein K63-linked Ubiquitination Regulation Of ATP Metabolic Process Regulation Of Cardiac Muscle Hypertrophy Endoplasmic Reticulum-Golgi Intermediate Compartment Immune Response Response To Interleukin-1 Regulation Of Purine Nucleotide Metabolic Process Response To External Biotic Stimulus Defense Response Regulation Of Non-canonical NF-kappaB Signal Transduction Protein K48-linked Ubiquitination Mononuclear Cell Migration