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POLM and PNMA1
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
POLM
PNMA1
Description
DNA polymerase mu
PNMA family member 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleus
Nucleolus
Cytoplasm
Molecular Function
DNA Binding
DNA-directed DNA Polymerase Activity
Protein Binding
Transferase Activity
Nucleotidyltransferase Activity
DNA Polymerase Activity
Metal Ion Binding
Protein Binding
Biological Process
DNA Repair
Double-strand Break Repair Via Nonhomologous End Joining
DNA Recombination
DNA Damage Response
Somatic Hypermutation Of Immunoglobulin Genes
B Cell Differentiation
DNA Biosynthetic Process
Inflammatory Response To Antigenic Stimulus
Positive Regulation Of Apoptotic Process
Pathways
Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS
Interacting Genes
14 interacting genes:
CEP55
CTAG1A
CTAG1B
IKZF3
OGT
PCNA
PNMA1
UBE2C
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2H
USHBP1
170 interacting genes:
ABHD17A
AGTR1
AIRIM
ANKRD36BP1
APTX
ARHGEF6
ARID5A
ASMTL
ATP5PO
ATP6V1G1
ATXN7
BEX2
BYSL
C21orf58
C8orf33
CARHSP1
CBX8
CCDC146
CCDC187
CCDC198
CCDC33
CCNG1
CCP110
CDK18
CFAP53
CFTR
CHIC2
CHMP2B
CNNM3
COX5B
CTNNA3
DAXX
DCTN4
EAF2
EHHADH
ENKD1
FAM107A
FAM110A
FAM161A
FAM161B
FBF1
FBXL18
FEM1C
FMNL2
FOXD4L1
FOXD4L3
FXR1
FXR2
GADD45GIP1
GATA1
GEM
GPANK1
GPR25
GRAP2
GTPBP10
HAPLN2
HCK
HDAC4
HGS
HNRNPLL
HOXB9
IGFN1
INO80B
IVD
KANSL1
KAT2B
LAGE3
LENG1
LIN37
LMO3
LNX1
LSM2
MAB21L2
MACIR
MARK4
MCM7
MED8
METTL17
MRPL10
MRPL11
MRPL23
MSI1
MYO15B
MYOZ1
NIF3L1
NPBWR2
NSMF
NTAQ1
NUDT16L1
PARD3
PARD6B
PCGF6
PER1
PIN1
PIN4
PKN1
PKN3
PNMA5
PNMA6A
POLDIP3
POLL
POLM
PRKAB2
PRKCG
PRKCI
PRPF18
PRPF31
PSMA1
RAD51D
RAPGEF3
RBM41
RPP25
RPP25L
RSPH9
RSRC2
RTP5
RUSC1
SCAND1
SCNM1
SDCBP
SEMA4C
SH2D4A
SHC3
SHISA3
SLC25A48
SLIRP
SMIM3
SNRPB
SNRPB2
SPATC1L
SPG7
SSX2IP
STAMBPL1
SUV39H2
TASOR2
TCEA2
TCEANC
TCL1B
TEAD4
TMSB4X
TNNI1
TNNT1
TRIM42
TRIM73
TRPV6
TSHZ2
TSPYL4
TTC23
TTC9C
TXNDC9
UBQLN1
UBQLN4
URB1-AS1
USP2
VAV2
VBP1
VPS9D1
WDR25
WT1-AS
ZC2HC1C
ZCCHC12
ZFYVE26
ZG16B
ZNF148
ZNF35
ZNF410
ZNF438
ZNF564
ZNF581
ZNF688
Entrez ID
27434
9240
HPRD ID
16208
04926
Ensembl ID
ENSG00000122678
ENSG00000176903
Uniprot IDs
Q9NP87
Q8ND90
PDB IDs
2DUN
2HTF
4LZD
4LZG
4M04
4M0A
4YCX
4YD1
4YD2
5TWP
5TWQ
5TWR
5TWS
5TXX
5TXZ
5TYB
5TYC
5TYD
5TYE
5TYF
5TYG
5TYU
5TYV
5TYW
5TYX
5TYY
5TYZ
5VZ7
5VZ8
5VZ9
5VZA
5VZB
5VZC
5VZD
5VZE
5VZF
5VZG
5VZH
5VZI
5W4F
5ZLC
6AEC
6AEH
6AK5
6AK6
6AK8
6AK9
6AKH
6IPD
6IPE
6IPF
6IPG
6IPH
6IPI
6IPJ
6IPK
6IPL
6IPM
6IPN
6P1M
6P1N
6P1O
6P1P
6P1Q
6P1R
6P1S
6P1T
6P1U
6P1V
6P1W
6VEZ
6VF0
6VF1
6VF2
6VF3
6VF4
6VF5
6VF6
6VF7
6VF8
6VF9
6VFA
6VFB
6VFC
6WIC
6WID
6WIE
7CO6
7CO8
7CO9
7COA
7COB
7COC
7COD
7KSS
7KST
7KSU
7KSV
7KSW
7KSX
7KSY
7KSZ
7KT0
7KT1
7KT2
7KT3
7KT4
7KT5
7KT6
7KT7
7KT8
7KT9
7KTA
7KTB
7KTC
7KTD
7KTE
7KTF
7KTG
7KTH
7KTI
7KTJ
7KTK
7KTL
7KTM
7KTN
Enriched GO Terms of Interacting Partners
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Ubiquitin Conjugating Enzyme Activity
Protein K48-linked Ubiquitination
Ubiquitin-protein Transferase Activity
Protein Polyubiquitination
Modification-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Protein K11-linked Ubiquitination
Proteolysis Involved In Protein Catabolic Process
Protein Modification By Small Protein Conjugation
Proteolysis
Post-translational Protein Modification
Macromolecule Catabolic Process
TRNA Threonylcarbamoyladenosine Metabolic Process
Protein Modification Process
Ubiquitin Protein Ligase Activity
Transferase Activity
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Catabolic Process
ATP Binding
Regulation Of Protein Ubiquitination
Proteasomal Protein Catabolic Process
PCNA Complex
Replisome
Protein N-acetylglucosaminyltransferase Complex
Negative Regulation Of Non-canonical Inflammasome Complex Assembly
Regulation Of Post-translational Protein Modification
Protein Monoubiquitination
Macromolecule Metabolic Process
Protein Catabolic Process
TORC1 Signaling
Negative Regulation Of BMP Signaling Pathway
PCNA-p21 Complex
DNA Polymerase Processivity Factor Activity
Purine-specific Mismatch Base Pair DNA N-glycosylase Activity
Nucleotide Binding
Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Protein Autoubiquitination
TOR Signaling
Mitotic Telomere Maintenance Via Semi-conservative Replication
Dinucleotide Insertion Or Deletion Binding
Regulation Of Cellular Response To Growth Factor Stimulus
Protein O-acetylglucosaminyltransferase Activity
Regulation Of TORC1 Signaling
Positive Regulation Of Deoxyribonuclease Activity
Leading Strand Elongation
ISG15 Transferase Activity
Positive Regulation Of Exit From Mitosis
Positive Regulation Of Protein Ubiquitination
Protein Binding
Nucleus
Diacylglycerol-dependent Serine/threonine Kinase Activity
PAR Polarity Complex
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Tagcloud (Difference)
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Tagcloud (Intersection)
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