PNMA1 and MYOZ1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PNMA1	MYOZ1
Description		PNMA family member 1	myozenin 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Nucleus Actin Cytoskeleton Z Disc Pseudopodium Cell Projection
	Molecular Function	Protein Binding	Actin Binding Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Telethonin Binding Actinin Binding FATZ Binding Molecular Condensate Scaffold Activity
	Biological Process	Inflammatory Response To Antigenic Stimulus Positive Regulation Of Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Skeletal Muscle Tissue Development Myofibril Assembly Wound Healing Negative Regulation Of Skeletal Muscle Tissue Regeneration Skeletal Muscle Fiber Adaptation Sarcomere Organization Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways
Drugs
Diseases
GWAS			Atrial fibrillation ( 30061737) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		170 interacting genes: ABHD17A AGTR1 AIRIM ANKRD36BP1 APTX ARHGEF6 ARID5A ASMTL ATP5PO ATP6V1G1 ATXN7 BEX2 BYSL C21orf58 C8orf33 CARHSP1 CBX8 CCDC146 CCDC187 CCDC198 CCDC33 CCNG1 CCP110 CDK18 CFAP53 CFTR CHIC2 CHMP2B CNNM3 COX5B CTNNA3 DAXX DCTN4 EAF2 EHHADH ENKD1 FAM107A FAM110A FAM161A FAM161B FBF1 FBXL18 FEM1C FMNL2 FOXD4L1 FOXD4L3 FXR1 FXR2 GADD45GIP1 GATA1 GEM GPANK1 GPR25 GRAP2 GTPBP10 HAPLN2 HCK HDAC4 HGS HNRNPLL HOXB9 IGFN1 INO80B IVD KANSL1 KAT2B LAGE3 LENG1 LIN37 LMO3 LNX1 LSM2 MAB21L2 MACIR MARK4 MCM7 MED8 METTL17 MRPL10 MRPL11 MRPL23 MSI1 MYO15B MYOZ1 NIF3L1 NPBWR2 NSMF NTAQ1 NUDT16L1 PARD3 PARD6B PCGF6 PER1 PIN1 PIN4 PKN1 PKN3 PNMA5 PNMA6A POLDIP3 POLL POLM PRKAB2 PRKCG PRKCI PRPF18 PRPF31 PSMA1 RAD51D RAPGEF3 RBM41 RPP25 RPP25L RSPH9 RSRC2 RTP5 RUSC1 SCAND1 SCNM1 SDCBP SEMA4C SH2D4A SHC3 SHISA3 SLC25A48 SLIRP SMIM3 SNRPB SNRPB2 SPATC1L SPG7 SSX2IP STAMBPL1 SUV39H2 TASOR2 TCEA2 TCEANC TCL1B TEAD4 TMSB4X TNNI1 TNNT1 TRIM42 TRIM73 TRPV6 TSHZ2 TSPYL4 TTC23 TTC9C TXNDC9 UBQLN1 UBQLN4 URB1-AS1 USP2 VAV2 VBP1 VPS9D1 WDR25 WT1-AS ZC2HC1C ZCCHC12 ZFYVE26 ZG16B ZNF148 ZNF35 ZNF410 ZNF438 ZNF564 ZNF581 ZNF688	42 interacting genes: ACTN1 ACTN2 ACTN3 ACTN4 AKAP8L APP BAG4 BRCA1 CEACAM6 CEP76 CRX EIF3F EXOSC8 FBXL21P FLNA FLNC GOLGA6A GRB2 GSK3B KRT34 KRT36 KRTAP12-2 LDB3 LHX4 LZTS2 MAGEA11 PFDN5 PLEKHG4 PNKP PNMA1 PRKAA2 TCAP TRAF1 TRIM23 TRIM55 TRIM63 USHBP1 VAC14 VBP1 WASHC3 WWOX YPEL3
Entrez ID		9240	58529
HPRD ID		04926	05725
Ensembl ID		ENSG00000176903	ENSG00000177791
Uniprot IDs		Q8ND90	Q9NP98
PDB IDs			7A8T 7A8U 7ANK
Enriched GO Terms of Interacting Partners?		Protein Binding Nucleus Diacylglycerol-dependent Serine/threonine Kinase Activity PAR Polarity Complex	Z Disc Pseudopodium Muscle Cell Development Actin Cytoskeleton Organization Actin Filament-based Process Regulation Of Apoptotic Process Transmembrane Transporter Binding Regulation Of Programmed Cell Death Identical Protein Binding Cytoskeleton Organization Sarcomere Organization Titin Binding Regulation Of Supramolecular Fiber Organization Titin Z Domain Binding Actin Filament Binding Regulation Of Glycolytic Process Cortical Actin Cytoskeleton Sarcomere Regulation Of Amyloid Fibril Formation Regulation Of Generation Of Precursor Metabolites And Energy Platelet Alpha Granule Lumen Regulation Of Carbohydrate Catabolic Process Cytoskeletal Protein Binding Integrin Binding Actin Binding Regulation Of ATP Metabolic Process Regulation Of Cytoskeleton Organization Focal Adhesion Assembly Cytosol Cytoplasm Actin Filament Positive Regulation Of Supramolecular Fiber Organization FATZ Binding Skeletal Muscle Atrophy Regulation Of Purine Nucleotide Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Cell-substrate Junction Assembly Skeletal Muscle Adaptation Striated Muscle Atrophy Prefoldin Complex Cell-substrate Junction Organization Anatomical Structure Morphogenesis Structural Constituent Of Muscle Actomyosin Structure Organization Supramolecular Fiber Organization Organelle Organization Muscle Atrophy Positive Regulation Of Organelle Organization Cell Development
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