POLM

Gene Name		polymerase (DNA directed), mu
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Gene Ontology Annotations	Cellular Component	Nucleoplasm
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Metal Ion Binding
	Biological Process	DNA Repair DNA Recombination Somatic Hypermutation Of Immunoglobulin Genes B Cell Differentiation DNA Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: CEP55 IKZF3 PCNA PNMA1 UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H
Entrez ID		27434
HPRD ID		16208
Ensembl ID		ENSG00000122678
Uniprot IDs		Q9NP87
PDB IDs		2DUN 2HTF
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Protein K11-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Cellular Macromolecule Catabolic Process Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Proteasomal Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ligase Activity Mitotic Cell Cycle Process Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Mitotic Cell Cycle Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of Protein Ubiquitination Toll-like Receptor Signaling Pathway
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