POLM and CEP55

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		POLM	CEP55
Gene Name		polymerase (DNA directed), mu	centrosomal protein 55kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Centrosome Centriole Membrane Midbody Cleavage Furrow Intercellular Bridge
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	DNA Repair DNA Recombination Somatic Hypermutation Of Immunoglobulin Genes B Cell Differentiation DNA Biosynthetic Process	Mitotic Cytokinesis Cell Separation After Cytokinesis Nucleus Organization Mitotic Metaphase Plate Congression Establishment Of Protein Localization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CEP55 IKZF3 PCNA PNMA1 UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H	55 interactors: AKAP9 ANXA11 ARHGEF15 C1orf109 CCBE1 CCDC53 CCHCR1 CDC45 CDK1 CDSN CEP57L1 DTNB ECSIT EIF1AD FAM90A1 FBF1 FXR2 GOLGA8DP HAUS1 HGS KIFC3 MAPK1 MAPK1IP1L MFAP1 MIA3 MORF4L2 MUM1 NOS3 PCNT PDCD6IP PEF1 PIN1 PLEKHG6 PLK1 POLM POM121 PPP1R16B PSEN2 PTPN23 RAB3D RBM17 RBM22 RCOR3 RNF32 SDCBP SNRPB SNW1 SSX2IP TCL1A TEAD4 TEX14 TFG TSG101 VPS37C VPS37D
Entrez ID		27434	55165
HPRD ID		16208	12569
Ensembl ID		ENSG00000122678	ENSG00000138180
Uniprot IDs		Q9NP87	Q53EZ4
PDB IDs		2DUN 2HTF	3E1R
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Protein K11-linked Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Cellular Macromolecule Catabolic Process Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Proteasomal Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ligase Activity Mitotic Cell Cycle Process Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Mitotic Cell Cycle Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of Protein Ubiquitination Toll-like Receptor Signaling Pathway	Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Protein Localization Establishment Of Protein Localization Virion Assembly Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Exocytosis Protein Transport Viral Protein Processing Positive Regulation Of Transport Mitotic Cell Cycle Process Regulation Of Vesicle-mediated Transport Cell Cycle Regulation Of Exocytosis Mitotic Cell Cycle Organelle Organization Cell Division Microtubule Cytoskeleton Organization Positive Regulation Of Extracellular Vesicular Exosome Assembly Intracellular Transport Of Virus Cell Cycle Process Regulation Of Cellular Localization Viral Life Cycle Centrosome Organization Membrane Organization Cellular Localization Mitotic Nuclear Envelope Disassembly Positive Regulation Of Metabolic Process Microtubule Organizing Center Organization Regulation Of Protein Metabolic Process Regulation Of Organelle Organization Anatomical Structure Development Nuclear Envelope Disassembly G2/M Transition Of Mitotic Cell Cycle Viral Process Microtubule-based Process Viral Budding Developmental Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Anatomical Structure Morphogenesis Cell Differentiation Regulation Of Signal Transduction Cellular Response To DNA Damage Stimulus Cell Projection Morphogenesis Regulation Of Early Endosome To Late Endosome Transport Cellular Protein Localization Cell Part Morphogenesis Regulation Of Cellular Component Organization Nuclear Envelope Organization
Tagcloud ?			atad2 birc5 cdkn2a cldn6 crypt ct26 epcam flt1 g12d gp70 hif1a homozygously immunome immunotherapies mabs mhc mki67 ms4a8a ms4a8b muc2 mutated nras pbk syngeneic synonymous top2a transcriptome trp53 undifferentiated
Tagcloud (Difference) ?			atad2 birc5 cdkn2a cldn6 crypt ct26 epcam flt1 g12d gp70 hif1a homozygously immunome immunotherapies mabs mhc mki67 ms4a8a ms4a8b muc2 mutated nras pbk syngeneic synonymous top2a transcriptome trp53 undifferentiated
Tagcloud (Intersection) ?