PNMA1 and TRPV6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PNMA1	TRPV6
Description		PNMA family member 1	transient receptor potential cation channel subfamily V member 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Plasma Membrane Membrane Calcium Channel Complex
	Molecular Function	Protein Binding	Monoatomic Ion Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Inflammatory Response To Antigenic Stimulus Positive Regulation Of Apoptotic Process	Monoatomic Ion Transport Calcium Ion Transport Regulation Of Calcium Ion-dependent Exocytosis Monoatomic Ion Transmembrane Transport Parathyroid Hormone Secretion Response To Calcium Ion Calcium Ion Homeostasis Transmembrane Transport Calcium Ion Transmembrane Transport Calcium Ion Import Across Plasma Membrane
Pathways			TRP channels
Drugs
Diseases
GWAS			Alcoholic chronic pancreatitis ( 28754779) Anxiety ( 31906708) Cancer ( 29299148) Mastocytosis ( 32752121)
Interacting Genes		170 interacting genes: ABHD17A AGTR1 AIRIM ANKRD36BP1 APTX ARHGEF6 ARID5A ASMTL ATP5PO ATP6V1G1 ATXN7 BEX2 BYSL C21orf58 C8orf33 CARHSP1 CBX8 CCDC146 CCDC187 CCDC198 CCDC33 CCNG1 CCP110 CDK18 CFAP53 CFTR CHIC2 CHMP2B CNNM3 COX5B CTNNA3 DAXX DCTN4 EAF2 EHHADH ENKD1 FAM107A FAM110A FAM161A FAM161B FBF1 FBXL18 FEM1C FMNL2 FOXD4L1 FOXD4L3 FXR1 FXR2 GADD45GIP1 GATA1 GEM GPANK1 GPR25 GRAP2 GTPBP10 HAPLN2 HCK HDAC4 HGS HNRNPLL HOXB9 IGFN1 INO80B IVD KANSL1 KAT2B LAGE3 LENG1 LIN37 LMO3 LNX1 LSM2 MAB21L2 MACIR MARK4 MCM7 MED8 METTL17 MRPL10 MRPL11 MRPL23 MSI1 MYO15B MYOZ1 NIF3L1 NPBWR2 NSMF NTAQ1 NUDT16L1 PARD3 PARD6B PCGF6 PER1 PIN1 PIN4 PKN1 PKN3 PNMA5 PNMA6A POLDIP3 POLL POLM PRKAB2 PRKCG PRKCI PRPF18 PRPF31 PSMA1 RAD51D RAPGEF3 RBM41 RPP25 RPP25L RSPH9 RSRC2 RTP5 RUSC1 SCAND1 SCNM1 SDCBP SEMA4C SH2D4A SHC3 SHISA3 SLC25A48 SLIRP SMIM3 SNRPB SNRPB2 SPATC1L SPG7 SSX2IP STAMBPL1 SUV39H2 TASOR2 TCEA2 TCEANC TCL1B TEAD4 TMSB4X TNNI1 TNNT1 TRIM42 TRIM73 TRPV6 TSHZ2 TSPYL4 TTC23 TTC9C TXNDC9 UBQLN1 UBQLN4 URB1-AS1 USP2 VAV2 VBP1 VPS9D1 WDR25 WT1-AS ZC2HC1C ZCCHC12 ZFYVE26 ZG16B ZNF148 ZNF35 ZNF410 ZNF438 ZNF564 ZNF581 ZNF688	17 interacting genes: CALB1 CALM1 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-8 MDFI MID2 NEDD4 NOTCH2NLA PDE9A PNMA1 PRKCA PTPN1 S100A10 SNCA TRAF1
Entrez ID		9240	55503
HPRD ID		04926	05982
Ensembl ID		ENSG00000176903	ENSG00000165125
Uniprot IDs		Q8ND90	Q9H1D0
PDB IDs			6BO8 6BO9 6BOA 6D7S 6D7T 6E2F 7K4A 7K4B 7K4C 7K4D 7K4E 7K4F 7S88 7S89 7S8B 7S8C 8FOA 8FOB 8SP8 9CUH 9CUI 9CUJ 9CUK
Enriched GO Terms of Interacting Partners?		Protein Binding Nucleus Diacylglycerol-dependent Serine/threonine Kinase Activity PAR Polarity Complex	Keratin Filament Intermediate Filament Regulation Of Synaptic Plasticity Regulation Of Cell Communication Regulation Of Signaling Enzyme Binding Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Exocytosis Regulation Of Cell Junction Assembly Positive Regulation Of Cell Communication Positive Regulation Of Signaling Calyx Of Held Regulation Of Signal Transduction Regulation Of Synapse Organization Calcium Ion Binding Presynaptic Cytosol Postsynaptic Cytosol Transmembrane Transporter Binding Regulation Of Intracellular Signal Transduction Positive Regulation Of Synaptic Transmission Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Metanephric Connecting Tubule Development Terminal Bouton Calcium Ion Binding Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Presynaptic Endocytosis Protein-containing Complex Identical Protein Binding Protein Sequestering Activity Receptor Metabolic Process Formation Of Structure Involved In A Symbiotic Process Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Synapse Assembly Regulation Of Exocytosis Response To Fibroblast Growth Factor Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Phosphoprotein Binding Cytosol Modulation Of Chemical Synaptic Transmission Long-term Synaptic Potentiation Postsynapse Calcium Ion Binding Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Muscle System Process Regulation Of System Process
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