POLM and CTAG1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		POLM	CTAG1B
Description		DNA polymerase mu	cancer/testis antigen 1B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasm
	Molecular Function	DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity DNA Polymerase Activity Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	DNA Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Recombination DNA Damage Response Somatic Hypermutation Of Immunoglobulin Genes B Cell Differentiation DNA Biosynthetic Process	TRNA Threonylcarbamoyladenosine Metabolic Process
Pathways		Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: CEP55 CTAG1A CTAG1B IKZF3 OGT PCNA PNMA1 UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H USHBP1	81 interacting genes: ACTN3 AIRIM ALOX15B ARHGEF28 ATP1A4 BAG6 BEX1 BEX2 BMF BORCS8 BORCS8-MEF2B C14orf119 CAMSAP1 CCDC116 CCHCR1 CDC37 CDKN2AIPNL CHCHD2 CSTF2T CTAG1A CYTH4 DESI1 FCHSD2 FSD2 GATC GNG13 GPSM3 GTF2I GUCD1 HCK HEMK1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 KIF26A KLHL38 LAMTOR1 LNPEP LONRF3 MAGEC1 MEIS2 MGAT5B MSGN1 NAB2 NCS1 NTAQ1 P4HA3 PEF1 PIH1D2 POLM PSMB1 RANBP10 REX1BD RSRC2 RTN4IP1 RUSC1 SEC14L4 SGTA SGTB SIKE1 SMG9 SOHLH1 SPAG8 STRA8 SUOX TCEANC TEPSIN THOC1 TNPO2 TRIB3 TRIM55 TRIM63 TSGA10IP UBE2V1 UBL5 UBQLN1 UBQLN2 USP20 VENTX WWOX
Entrez ID		27434	1485
HPRD ID		16208	02151
Ensembl ID		ENSG00000122678	ENSG00000184033
Uniprot IDs		Q9NP87	P78358
PDB IDs		2DUN 2HTF 4LZD 4LZG 4M04 4M0A 4YCX 4YD1 4YD2 5TWP 5TWQ 5TWR 5TWS 5TXX 5TXZ 5TYB 5TYC 5TYD 5TYE 5TYF 5TYG 5TYU 5TYV 5TYW 5TYX 5TYY 5TYZ 5VZ7 5VZ8 5VZ9 5VZA 5VZB 5VZC 5VZD 5VZE 5VZF 5VZG 5VZH 5VZI 5W4F 5ZLC 6AEC 6AEH 6AK5 6AK6 6AK8 6AK9 6AKH 6IPD 6IPE 6IPF 6IPG 6IPH 6IPI 6IPJ 6IPK 6IPL 6IPM 6IPN 6P1M 6P1N 6P1O 6P1P 6P1Q 6P1R 6P1S 6P1T 6P1U 6P1V 6P1W 6VEZ 6VF0 6VF1 6VF2 6VF3 6VF4 6VF5 6VF6 6VF7 6VF8 6VF9 6VFA 6VFB 6VFC 6WIC 6WID 6WIE 7CO6 7CO8 7CO9 7COA 7COB 7COC 7COD 7KSS 7KST 7KSU 7KSV 7KSW 7KSX 7KSY 7KSZ 7KT0 7KT1 7KT2 7KT3 7KT4 7KT5 7KT6 7KT7 7KT8 7KT9 7KTA 7KTB 7KTC 7KTD 7KTE 7KTF 7KTG 7KTH 7KTI 7KTJ 7KTK 7KTL 7KTM 7KTN	1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG 6RP9 6RPA 6RPB 9C3E 9DL1
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein K48-linked Ubiquitination Ubiquitin-protein Transferase Activity Protein Polyubiquitination Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein K11-linked Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Proteolysis Post-translational Protein Modification Macromolecule Catabolic Process TRNA Threonylcarbamoyladenosine Metabolic Process Protein Modification Process Ubiquitin Protein Ligase Activity Transferase Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Catabolic Process ATP Binding Regulation Of Protein Ubiquitination Proteasomal Protein Catabolic Process PCNA Complex Replisome Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Post-translational Protein Modification Protein Monoubiquitination Macromolecule Metabolic Process Protein Catabolic Process TORC1 Signaling Negative Regulation Of BMP Signaling Pathway PCNA-p21 Complex DNA Polymerase Processivity Factor Activity Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Nucleotide Binding Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein Autoubiquitination TOR Signaling Mitotic Telomere Maintenance Via Semi-conservative Replication Dinucleotide Insertion Or Deletion Binding Regulation Of Cellular Response To Growth Factor Stimulus Protein O-acetylglucosaminyltransferase Activity Regulation Of TORC1 Signaling Positive Regulation Of Deoxyribonuclease Activity Leading Strand Elongation ISG15 Transferase Activity Positive Regulation Of Exit From Mitosis Positive Regulation Of Protein Ubiquitination	Protein Binding Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Positive Regulation Of ERAD Pathway Antigen Processing And Presentation Of Exogenous Antigen Regulation Of ERAD Pathway MHC Class II Protein Complex Binding ER To Golgi Transport Vesicle Membrane Lumenal Side Of Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Peptide Antigen Binding TRC Complex Positive Regulation Of Response To Endoplasmic Reticulum Stress Myeloid Dendritic Cell Antigen Processing And Presentation Transport Vesicle Membrane Antigen Processing And Presentation Trans-Golgi Network Membrane Skeletal Muscle Atrophy Dendritic Cell Antigen Processing And Presentation Positive Regulation Of Proteasomal Protein Catabolic Process Clathrin-coated Endocytic Vesicle Membrane Protein Targeting To ER Regulation Of Protein Ubiquitination Skeletal Muscle Adaptation Striated Muscle Atrophy Lysosomal Membrane Endocytic Vesicle Membrane Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Autolysosome Membrane Muscle Atrophy Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell MHC Class II Receptor Activity Polyubiquitin Modification-dependent Protein Binding Late Endosome Membrane Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Regulation Of Post-translational Protein Modification
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