PNMA1 and ZCCHC12

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		PNMA1	ZCCHC12
Description		PNMA family member 1	zinc finger CCHC-type containing 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Nucleus
	Molecular Function	Protein Binding	Nucleic Acid Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Inflammatory Response To Antigenic Stimulus Positive Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Interacting Genes		170 interacting genes: ABHD17A AGTR1 AIRIM ANKRD36BP1 APTX ARHGEF6 ARID5A ASMTL ATP5PO ATP6V1G1 ATXN7 BEX2 BYSL C21orf58 C8orf33 CARHSP1 CBX8 CCDC146 CCDC187 CCDC198 CCDC33 CCNG1 CCP110 CDK18 CFAP53 CFTR CHIC2 CHMP2B CNNM3 COX5B CTNNA3 DAXX DCTN4 EAF2 EHHADH ENKD1 FAM107A FAM110A FAM161A FAM161B FBF1 FBXL18 FEM1C FMNL2 FOXD4L1 FOXD4L3 FXR1 FXR2 GADD45GIP1 GATA1 GEM GPANK1 GPR25 GRAP2 GTPBP10 HAPLN2 HCK HDAC4 HGS HNRNPLL HOXB9 IGFN1 INO80B IVD KANSL1 KAT2B LAGE3 LENG1 LIN37 LMO3 LNX1 LSM2 MAB21L2 MACIR MARK4 MCM7 MED8 METTL17 MRPL10 MRPL11 MRPL23 MSI1 MYO15B MYOZ1 NIF3L1 NPBWR2 NSMF NTAQ1 NUDT16L1 PARD3 PARD6B PCGF6 PER1 PIN1 PIN4 PKN1 PKN3 PNMA5 PNMA6A POLDIP3 POLL POLM PRKAB2 PRKCG PRKCI PRPF18 PRPF31 PSMA1 RAD51D RAPGEF3 RBM41 RPP25 RPP25L RSPH9 RSRC2 RTP5 RUSC1 SCAND1 SCNM1 SDCBP SEMA4C SH2D4A SHC3 SHISA3 SLC25A48 SLIRP SMIM3 SNRPB SNRPB2 SPATC1L SPG7 SSX2IP STAMBPL1 SUV39H2 TASOR2 TCEA2 TCEANC TCL1B TEAD4 TMSB4X TNNI1 TNNT1 TRIM42 TRIM73 TRPV6 TSHZ2 TSPYL4 TTC23 TTC9C TXNDC9 UBQLN1 UBQLN4 URB1-AS1 USP2 VAV2 VBP1 VPS9D1 WDR25 WT1-AS ZC2HC1C ZCCHC12 ZFYVE26 ZG16B ZNF148 ZNF35 ZNF410 ZNF438 ZNF564 ZNF581 ZNF688	27 interacting genes: ABHD5 APP APPBP2 ATP6V0C CD207 FADD FATE1 KPNA3 LMO1 MAGEA11 MCRS1 MX1 PNMA1 PRMT1 RNF40 RUSF1 SPOP STX2 SUMO1 SUMO2 SUMO3 TADA2A TFCP2 TMEM43 TMEM79 TNF UBE2I
Entrez ID		9240	170261
HPRD ID		04926	06616
Ensembl ID		ENSG00000176903	ENSG00000174460
Uniprot IDs		Q8ND90	Q6PEW1
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Nucleus Diacylglycerol-dependent Serine/threonine Kinase Activity PAR Polarity Complex	Protein Sumoylation Protein Tag Activity Transcription Factor Binding Ubiquitin Protein Ligase Binding Ubiquitin-like Protein Ligase Binding Presynaptic Cytosol Postsynaptic Cytosol Positive Regulation Of Proteolysis Regulation Of Proteolysis PML Body Small Protein Activating Enzyme Binding Protein Modification By Small Protein Conjugation Necroptotic Signaling Pathway Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Protein Localization To Nucleus Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Type II Interferon Production Identical Protein Binding Post-translational Protein Modification Nucleoplasm Positive Regulation Of Membrane Protein Ectodomain Proteolysis Positive Regulation Of Protein Catabolic Process Nuclear Pore Astrocyte Activation Negative Regulation Of DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Amyloid-beta Clearance SUMO Transferase Activity Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lipid Storage Negative Regulation Of Blood Circulation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein Modification Process Positive Regulation Of Myeloid Cell Differentiation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Membrane Protein Ectodomain Proteolysis Negative Regulation Of MiRNA Transcription Regulation Of Type II Interferon Production Regulation Of RNA Metabolic Process Microglial Cell Activation Defense Response To Virus Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Catabolic Process Regulation Of JNK Cascade
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