DESI1 and CCDC158

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DESI1	CCDC158
Description		desumoylating isopeptidase 1	coiled-coil domain containing 158
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Protein-containing Complex	Early Endosome Clathrin-coated Vesicle
	Molecular Function	Protein Binding Peptidase Activity Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity DeSUMOylase Activity Identical Protein Binding Long-chain Fatty Acyl-CoA Hydrolase Activity Importin-alpha Family Protein Binding	Protein Binding Clathrin Binding
	Biological Process	Proteolysis Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Macromolecule Depalmitoylation	Receptor-mediated Endocytosis
Pathways
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)	Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31015462)
Interacting Genes		32 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RNF4 RPS27A SHISA4 SHISA5 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLNL UHRF2 XPO1 ZBTB46	11 interacting genes: C1orf216 DESI1 FCHSD2 GPSM1 NAGK NUTF2 SGF29 SH3GLB2 TBC1D21 TNPO2 UBQLN2
Entrez ID		27351	339965
HPRD ID		18590	13395
Ensembl ID		ENSG00000100418	ENSG00000163749
Uniprot IDs		Q6ICB0	A0A804HIY6 Q5M9N0
PDB IDs		3EBQ
Enriched GO Terms of Interacting Partners?		Protein Tag Activity TRNA Threonylcarbamoyladenosine Metabolic Process Modification-dependent Protein Catabolic Process Endocytic Vesicle Membrane Ubiquitin Protein Ligase Binding Mitochondrial Outer Membrane Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Regulation Of Granulocyte Differentiation Protein Modification By Small Protein Conjugation Vesicle	Nuclear Import Signal Receptor Activity Stereocilium Shaft Establishment Of Protein Localization Nuclear Transport Nucleocytoplasmic Transport Small GTPase Binding Protein Export From Nucleus N-acetylglucosamine Kinase Activity Muramyl Dipeptide Kinase Activity Establishment Of Protein Localization To Organelle Negative Regulation Of G Protein-coupled Receptor Internalization N-acylmannosamine Kinase Activity N-acetylmannosamine Metabolic Process
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