DESI1 and UBQLNL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DESI1	UBQLNL
Description		desumoylating isopeptidase 1	ubiquilin like
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Protein-containing Complex	Cytosol
	Molecular Function	Protein Binding Peptidase Activity Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity DeSUMOylase Activity Identical Protein Binding Long-chain Fatty Acyl-CoA Hydrolase Activity Importin-alpha Family Protein Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Proteolysis Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Macromolecule Depalmitoylation	Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)	Malaria ( 31844061)
Interacting Genes		32 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RNF4 RPS27A SHISA4 SHISA5 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLNL UHRF2 XPO1 ZBTB46	3 interacting genes: DESI1 HGS LMNA
Entrez ID		27351	143630
HPRD ID		18590	14472
Ensembl ID		ENSG00000100418	ENSG00000175518
Uniprot IDs		Q6ICB0	Q8IYU4
PDB IDs		3EBQ
Enriched GO Terms of Interacting Partners?		Protein Tag Activity TRNA Threonylcarbamoyladenosine Metabolic Process Modification-dependent Protein Catabolic Process Endocytic Vesicle Membrane Ubiquitin Protein Ligase Binding Mitochondrial Outer Membrane Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Regulation Of Granulocyte Differentiation Protein Modification By Small Protein Conjugation Vesicle	Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Lamin Filament DNA Double-strand Break Attachment To Nuclear Envelope Nuclear Transport Nucleocytoplasmic Transport Cellular Localization Protein Transport Establishment Of Protein Localization Ventricular Cardiac Muscle Cell Development Nuclear Pore Localization Establishment Of Protein Localization To Organelle Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Mesenchymal Cell Proliferation Establishment Of Localization In Cell Intracellular Transport Intracellular Protein Transport Structural Constituent Of Nuclear Lamina ESCRT-0 Complex Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Phagocytic Vesicle Lumen Regulation Of Protein Catabolic Process Macromolecule Depalmitoylation DeSUMOylase Activity Importin-alpha Family Protein Binding Palmitoyl-(protein) Hydrolase Activity Protein Desumoylation Inner Dynein Arm Nuclear Lamina Protein Localization To Nuclear Envelope Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Exosomal Secretion Long-chain Fatty Acyl-CoA Hydrolase Activity Minus-end-directed Microtubule Motor Activity Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Protein Localization Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Exosomal Secretion Sperm Flagellum Assembly Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Localization Within Membrane Nuclear Envelope Organization Nuclear Migration Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Ubiquitin-like Protein Ligase Binding Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Macromolecule Deacylation Dynein Light Intermediate Chain Binding Multivesicular Body Membrane Negative Regulation Of Receptor Signaling Pathway Via STAT
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?