DESI1 and CDIP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DESI1	CDIP1
Description		desumoylating isopeptidase 1	cell death inducing p53 target 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Protein-containing Complex	Nucleus Lysosome Lysosomal Membrane Endosome Membrane Late Endosome Membrane Cytoplasmic Side Of Late Endosome Membrane Cytoplasmic Side Of Lysosomal Membrane
	Molecular Function	Protein Binding Peptidase Activity Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity DeSUMOylase Activity Identical Protein Binding Long-chain Fatty Acyl-CoA Hydrolase Activity Importin-alpha Family Protein Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Proteolysis Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Macromolecule Depalmitoylation	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Pathways
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)	A body shape index ( 34021172) Eosinophil percentage of white cells ( 32888494) Femur bone mineral density x serum urate levels interaction ( 34046847) Hip circumference adjusted for BMI ( 34021172) Schizophrenia ( 28991256) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		32 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RNF4 RPS27A SHISA4 SHISA5 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLNL UHRF2 XPO1 ZBTB46	16 interacting genes: ATXN1 CCR2 DCUN1D1 DESI1 EPN2 LAT NEDD4 OTUB2 OTUD7B TNIP1 TOLLIP UBB UBC UBQLN1 UBQLN2 YAP1
Entrez ID		27351	29965
HPRD ID		18590	12676
Ensembl ID		ENSG00000100418	ENSG00000089486
Uniprot IDs		Q6ICB0	Q9H305
PDB IDs		3EBQ
Enriched GO Terms of Interacting Partners?		Protein Tag Activity TRNA Threonylcarbamoyladenosine Metabolic Process Modification-dependent Protein Catabolic Process Endocytic Vesicle Membrane Ubiquitin Protein Ligase Binding Mitochondrial Outer Membrane Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Regulation Of Granulocyte Differentiation Protein Modification By Small Protein Conjugation Vesicle	Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Metabolic Process Proteolysis Positive Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Regulation Of Post-translational Protein Modification Post-translational Protein Modification Protein Metabolic Process Modification-dependent Protein Catabolic Process Regulation Of Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Macromolecule Metabolic Process Regulation Of Protein Modification Process Regulation Of Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Regulation Of Proteasomal Protein Catabolic Process Protein K11-linked Deubiquitination Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Cytosol Regulation Of Macromolecule Metabolic Process Protein Tag Activity Ubiquitin Binding Proline-rich Region Binding Positive Regulation Of ERAD Pathway Negative Regulation Of Signal Transduction Regulation Of Primary Metabolic Process Cytoplasm Protein Modification By Small Protein Removal Regulation Of Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Macromolecule Catabolic Process Regulation Of ERAD Pathway Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Positive Regulation Of Signal Transduction Protein Modification Process Regulation Of Proteolysis Ubiquitin Conjugating Enzyme Binding Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein-containing Complex Negative Regulation Of Transport Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Macroautophagy
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