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TUBG2 and PXN
Number of citations of the paper that reports this interaction (PMID
10840040
)
18
Data Source:
HPRD
(in vitro, in vivo)
TUBG2
PXN
Gene Name
tubulin, gamma 2
paxillin
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Pericentriolar Material
Gamma-tubulin Complex
Cytosol
Microtubule
Spindle Microtubule
Cytoplasmic Microtubule
Microtubule Cytoskeleton
Stress Fiber
Nucleoplasm
Cytoplasm
Cytosol
Microtubule Associated Complex
Plasma Membrane
Focal Adhesion
Cell Cortex
Lamellipodium
Molecular Function
GTPase Activity
Structural Molecule Activity
GTP Binding
Integrin Binding
Protein Binding
Beta-catenin Binding
Zinc Ion Binding
Vinculin Binding
Protein Kinase Binding
BH4 Domain Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Microtubule Nucleation
Cytoplasmic Microtubule Organization
Activation Of MAPK Activity
Movement Of Cell Or Subcellular Component
Muscle Contraction
Cytoskeleton Organization
Cell Adhesion
Signal Transduction
Signal Complex Assembly
Epidermal Growth Factor Receptor Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Integrin-mediated Signaling Pathway
Regulation Of Cell Shape
Peptidyl-tyrosine Phosphorylation
Lamellipodium Assembly
Cell Junction Assembly
Substrate Adhesion-dependent Cell Spreading
Cellular Response To Reactive Oxygen Species
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Focal Adhesion Assembly
Branching Morphogenesis Of An Epithelial Tube
Growth Hormone Receptor Signaling Pathway
Pathways
G2/M Transition
Centrosome maturation
Mitotic G2-G2/M phases
Recruitment of NuMA to mitotic centrosomes
Cell Cycle, Mitotic
Recruitment of mitotic centrosome proteins and complexes
Cell junction organization
GAB1 signalosome
Smooth Muscle Contraction
Signaling by Ligand-Responsive EGFR Variants in Cancer
Signaling by EGFRvIII in Cancer
Signaling by Overexpressed Wild-Type EGFR in Cancer
VEGFA-VEGFR2 Pathway
Signaling by EGFR
Signaling by VEGF
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Signaling by EGFR in Cancer
Localization of the PINCH-ILK-PARVIN complex to focal adhesions
Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
PXN
RNF19A
TUBGCP3
73 interactors:
ABL1
AHCY
AR
ARHGEF7
ASAP1
ASAP2
BCAR1
BCL2
CASP3
CEACAM1
CLTC
CREB3L2
CRK
CRKL
CSK
DGUOK
EPHB1
FYN
GART
GIT1
GIT2
GRB2
GSK3A
GSK3B
GSN
HDAC6
ILK
ITGA4
ITGA6
ITGA9
ITGB1
ITGB3
LCK
LIMK1
MAPK1
MAPK3
MAPK8
MATK
NCK1
NEDD9
NF2
PABPC1
PAK1
PAK3
PARVA
PDPK1
PKD1
POLR1D
PPP2CA
PPP2R5C
PTEN
PTK2
PTK2B
PTPN11
PTPN12
PTPRH
RASA1
REPS2
RNF5
SDC4
SELE
SORBS1
SRC
SYK
TLN1
TRIP6
TUBA1B
TUBA3C
TUBA8
TUBG1
TUBG2
VCL
XPO1
Entrez ID
27175
5829
HPRD ID
05778
03937
Ensembl ID
ENSG00000037042
ENSG00000089159
Uniprot IDs
Q9NRH3
E7EMK8
F5GZ78
P49023
PDB IDs
1KKY
1KL0
1OW6
1OW7
1OW8
2K2R
2O9V
2VZD
2VZG
2VZI
3GM1
3PY7
3RQE
3RQF
3RQG
3U3C
3U3F
4EDN
Enriched GO Terms of Interacting Partners
?
Cytoskeleton Organization
Cellular Protein Complex Assembly
Microtubule Cytoskeleton Organization
Signal Complex Assembly
Cellular Macromolecular Complex Assembly
Microtubule Nucleation
Organelle Organization
Microtubule Polymerization
Growth Hormone Receptor Signaling Pathway
Microtubule-based Process
Cellular Response To Growth Hormone Stimulus
Focal Adhesion Assembly
Microtubule Polymerization Or Depolymerization
Response To Growth Hormone
Substrate Adhesion-dependent Cell Spreading
Protein Complex Assembly
Adherens Junction Assembly
Lamellipodium Assembly
Cell-substrate Junction Assembly
Lamellipodium Organization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Cellular Component Organization
Locomotion
Movement Of Cell Or Subcellular Component
Regulation Of Cell Adhesion
Cell Morphogenesis Involved In Differentiation
Response To Wounding
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Wound Healing
Blood Coagulation
Regulation Of Phosphorylation
Hemostasis
Cell Migration
Response To External Stimulus
Cell Projection Morphogenesis
Axonogenesis
Cell Part Morphogenesis
Cell Morphogenesis
Immune System Process
Immune Response-regulating Signaling Pathway
Neuron Projection Morphogenesis
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Cell Motility
Positive Regulation Of Catalytic Activity
Axon Development
Anatomical Structure Morphogenesis
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Signal Transduction
Regulation Of Protein Kinase Activity
Cell Surface Receptor Signaling Pathway
Cell Projection Organization
Regulation Of Phosphorus Metabolic Process
Regulation Of Intracellular Signal Transduction
Fc Receptor Signaling Pathway
Integrin-mediated Signaling Pathway
Axon Guidance
Positive Regulation Of Phosphorylation
Regulation Of Protein Phosphorylation
Chemotaxis
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Catalytic Activity
Regulation Of Kinase Activity
Neuron Projection Development
Response To Stress
Positive Regulation Of Protein Phosphorylation
Signal Transduction
Cell-substrate Adhesion
Tagcloud
?
acclimatized
adra1d
altitude
araf
argef11
arhgap24
ascent
cardiogenic
circuitry
cldn23
cldn6
ece1
ednra
genic
hape
inciting
map2k2
map2k7
mapk10
mylk
oxphos
pak3
pathoetiology
plcb1
skew
sos1
unacclimatized
vasoconstriction
vcam1
Tagcloud (Difference)
?
acclimatized
adra1d
altitude
araf
argef11
arhgap24
ascent
cardiogenic
circuitry
cldn23
cldn6
ece1
ednra
genic
hape
inciting
map2k2
map2k7
mapk10
mylk
oxphos
pak3
pathoetiology
plcb1
skew
sos1
unacclimatized
vasoconstriction
vcam1
Tagcloud (Intersection)
?