CIDEB and PDHX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CIDEB	PDHX
Description		cell death inducing DFFA like effector b	pyruvate dehydrogenase complex component X
Image
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Membrane COPII Vesicle Coat COPI-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	Nucleoplasm Mitochondrion Mitochondrial Matrix Plasma Membrane Pyruvate Dehydrogenase Complex
	Molecular Function	Protein Binding Identical Protein Binding Molecular Adaptor Activity Phosphatidic Acid Binding Lipid Transfer Activity	Dihydrolipoyllysine-residue Acetyltransferase Activity Protein Binding Acyltransferase Activity
	Biological Process	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Lipid Storage Response To Nutrient Levels Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Apoptotic Process COPII-coated Vesicle Cargo Loading Regulation Of Triglyceride Metabolic Process Execution Phase Of Apoptosis Intermembrane Lipid Transfer Lipid Droplet Fusion	Pyruvate Decarboxylation To Acetyl-CoA
Pathways			Regulation of pyruvate dehydrogenase (PDH) complex Signaling by Retinoic Acid PDH complex synthesizes acetyl-CoA from PYR
Drugs
Diseases			Pyruvate dehydrogenase complex deficiency; X-linked Leigh syndrome
GWAS		Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)	Bone mineral density (hip) ( 30172743) Heel bone mineral density ( 30598549) Systemic lupus erythematosus ( 28714469) Type 2 diabetes ( 30297969) Uterine fibroids ( 30194396 31649266)
Interacting Genes		68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C IRX2-DT MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1	11 interacting genes: ACTN1 AGTRAP CIDEB DLAT DLD EP300 EWSR1 HSD17B10 OGT PDHB PDK2
Entrez ID		27141	8050
HPRD ID		11981	02002
Ensembl ID		ENSG00000136305	ENSG00000110435
Uniprot IDs		Q9UHD4	A0A8C8MSB2 O00330
PDB IDs		1D4B	1ZY8 2DNC 2F5Z 2F60 6H60
Enriched GO Terms of Interacting Partners?		Mitochondrion Mitochondrial Inner Membrane Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Apoptotic DNA Fragmentation High-density Lipoprotein Particle Protein Binding Mitochondrion Organization Mitochondrial Membrane Copper Chaperone Activity Disordered Domain Specific Binding T Cell Apoptotic Process Mitochondrial Matrix Organophosphate Biosynthetic Process Cytochrome Complex Assembly Pyruvate Decarboxylation To Acetyl-CoA Activation-induced Cell Death Of T Cells Mitochondrial Respiratory Chain Complex Assembly Lymphocyte Apoptotic Process Import Into The Mitochondrion Negative Regulation Of Execution Phase Of Apoptosis Protein Localization To Mitochondrion	Pyruvate Dehydrogenase Complex Pyruvate Decarboxylation To Acetyl-CoA Acetyl-CoA Biosynthetic Process Pyruvate Metabolic Process Acetyl-CoA Metabolic Process Glucose Metabolic Process Hexose Metabolic Process Mitochondrial Matrix Monosaccharide Metabolic Process Regulation Of Gluconeogenesis Monocarboxylic Acid Metabolic Process Acyl-CoA Metabolic Process Sulfur Compound Biosynthetic Process Regulation Of Glucose Metabolic Process Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Acetyltransferase Activity Branched-chain Amino Acid Catabolic Process Carbohydrate Metabolic Process Amide Biosynthetic Process Platelet Formation Small Molecule Metabolic Process Histone Acetyltransferase Complex Branched-chain Amino Acid Metabolic Process Purine-containing Compound Metabolic Process Intrinsic Apoptotic Signaling Pathway Tricarboxylic Acid Cycle Response To Nutrient Levels Mitochondrion Cellular Response To Nutrient Nucleoside Phosphate Metabolic Process Carboxylic Acid Catabolic Process Purine-containing Compound Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process Sulfur Compound Metabolic Process Dihydrolipoyl Dehydrogenase (NADH) Activity 2-oxoglutarate Decarboxylation To Succinyl-CoA Acetyltransferase Complex Peptidyl-lysine Propionylation Regulation Of Glycolytic Process Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Cellular Response To Nutrient Levels Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Histone Crotonyltransferase Activity Isoursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?