CIDEB and AFG1L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CIDEB	AFG1L
Description		cell death inducing DFFA like effector b	AFG1 like ATPase
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Membrane COPII Vesicle Coat COPI-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	Cytoplasm Mitochondrion Membrane Mitochondrial Membrane
	Molecular Function	Protein Binding Identical Protein Binding Molecular Adaptor Activity Phosphatidic Acid Binding Lipid Transfer Activity	Nucleotide Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity
	Biological Process	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Lipid Storage Response To Nutrient Levels Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Apoptotic Process COPII-coated Vesicle Cargo Loading Regulation Of Triglyceride Metabolic Process Execution Phase Of Apoptosis Intermembrane Lipid Transfer Lipid Droplet Fusion	Mitochondrion Organization Mitochondrial Protein Catabolic Process Mitochondrial Protein Quality Control
Pathways
Drugs
Diseases
GWAS		Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C IRX2-DT MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1	2 interacting genes: BANP CIDEB
Entrez ID		27141	246269
HPRD ID		11981	11223
Ensembl ID		ENSG00000136305	ENSG00000135537
Uniprot IDs		Q9UHD4	Q8WV93
PDB IDs		1D4B
Enriched GO Terms of Interacting Partners?		Mitochondrion Mitochondrial Inner Membrane Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Apoptotic DNA Fragmentation High-density Lipoprotein Particle Protein Binding Mitochondrion Organization Mitochondrial Membrane Copper Chaperone Activity Disordered Domain Specific Binding T Cell Apoptotic Process Mitochondrial Matrix Organophosphate Biosynthetic Process Cytochrome Complex Assembly Pyruvate Decarboxylation To Acetyl-CoA Activation-induced Cell Death Of T Cells Mitochondrial Respiratory Chain Complex Assembly Lymphocyte Apoptotic Process Import Into The Mitochondrion Negative Regulation Of Execution Phase Of Apoptosis Protein Localization To Mitochondrion	Radial Spoke Head 2 Maintenance Of Ciliary Planar Beating Movement Pattern Radial Spoke Head 1 Radial Spoke Assembly Radial Spoke Head 3 Lipid Droplet Fusion Radial Spoke Head COPI-coated Vesicle Lipid Transfer Activity Very-low-density Lipoprotein Particle Assembly Radial Spoke COPII Vesicle Coat COPII-coated Vesicle Cargo Loading Execution Phase Of Apoptosis Phosphatidic Acid Binding Protein-lipid Complex Assembly Plasma Lipoprotein Particle Assembly Lipid Storage Intermembrane Lipid Transfer Vesicle Cargo Loading 9+2 Motile Cilium Regulation Of Cilium Movement Lipid Droplet Organization Regulation Of Triglyceride Metabolic Process Axoneme Assembly Extracellular Transport Epithelial Cilium Movement Involved In Extracellular Fluid Movement Regulation Of Microtubule-based Movement Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
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