CIDEB and FUNDC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CIDEB	FUNDC2
Description		cell death inducing DFFA like effector b	FUN14 domain containing 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Membrane COPII Vesicle Coat COPI-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	Nucleus Mitochondrion Mitochondrial Outer Membrane Membrane
	Molecular Function	Protein Binding Identical Protein Binding Molecular Adaptor Activity Phosphatidic Acid Binding Lipid Transfer Activity	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding
	Biological Process	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Lipid Storage Response To Nutrient Levels Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Apoptotic Process COPII-coated Vesicle Cargo Loading Regulation Of Triglyceride Metabolic Process Execution Phase Of Apoptosis Intermembrane Lipid Transfer Lipid Droplet Fusion	Autophagy Of Mitochondrion Regulation Of Platelet Activation Intracellular Triglyceride Homeostasis
Pathways
Drugs
Diseases
GWAS		Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C IRX2-DT MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1	40 interacting genes: AQP6 ARL13B ARL15 ASCC2 ATP13A2 CD79A CIDEB COX20 CRB3 CYB5R3 EBP EIF6 ERGIC3 EVI2B FAM209A FCER1G FGF14 GPR152 KCNJ6 KIR2DL3 MGST3 NACA NSF NUDT21 REEP4 RETREG3 RGS1 SAT1 SDR16C5 SLC10A6 SLC16A10 SLC66A2 SLC71A2 STOM SYT2 TMEM14B TMEM154 TMX2 TP53I3 USP13
Entrez ID		27141	65991
HPRD ID		11981	06586
Ensembl ID		ENSG00000136305	ENSG00000165775
Uniprot IDs		Q9UHD4	Q9BWH2
PDB IDs		1D4B
Enriched GO Terms of Interacting Partners?		Mitochondrion Mitochondrial Inner Membrane Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Apoptotic DNA Fragmentation High-density Lipoprotein Particle Protein Binding Mitochondrion Organization Mitochondrial Membrane Copper Chaperone Activity Disordered Domain Specific Binding T Cell Apoptotic Process Mitochondrial Matrix Organophosphate Biosynthetic Process Cytochrome Complex Assembly Pyruvate Decarboxylation To Acetyl-CoA Activation-induced Cell Death Of T Cells Mitochondrial Respiratory Chain Complex Assembly Lymphocyte Apoptotic Process Import Into The Mitochondrion Negative Regulation Of Execution Phase Of Apoptosis Protein Localization To Mitochondrion	Membrane
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