CIDEB and MRPL36

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CIDEB	MRPL36
Description		cell death inducing DFFA like effector b	mitochondrial ribosomal protein L36
Image
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Membrane COPII Vesicle Coat COPI-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Ribosome Nuclear Body Ribonucleoprotein Complex
	Molecular Function	Protein Binding Identical Protein Binding Molecular Adaptor Activity Phosphatidic Acid Binding Lipid Transfer Activity	Structural Constituent Of Ribosome Protein Binding
	Biological Process	Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Lipid Storage Response To Nutrient Levels Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Apoptotic Process COPII-coated Vesicle Cargo Loading Regulation Of Triglyceride Metabolic Process Execution Phase Of Apoptosis Intermembrane Lipid Transfer Lipid Droplet Fusion	Translation Mitochondrial Translation
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)	Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627)
Interacting Genes		68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C IRX2-DT MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1	2 interacting genes: CIDEB RRAS
Entrez ID		27141	64979
HPRD ID		11981	14756
Ensembl ID		ENSG00000136305	ENSG00000171421
Uniprot IDs		Q9UHD4	Q9P0J6
PDB IDs		1D4B	3J7Y 3J9M 5OOL 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OIC 7OID 7OIE 7PD3 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8QSJ 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?		Mitochondrion Mitochondrial Inner Membrane Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Apoptotic DNA Fragmentation High-density Lipoprotein Particle Protein Binding Mitochondrion Organization Mitochondrial Membrane Copper Chaperone Activity Disordered Domain Specific Binding T Cell Apoptotic Process Mitochondrial Matrix Organophosphate Biosynthetic Process Cytochrome Complex Assembly Pyruvate Decarboxylation To Acetyl-CoA Activation-induced Cell Death Of T Cells Mitochondrial Respiratory Chain Complex Assembly Lymphocyte Apoptotic Process Import Into The Mitochondrion Negative Regulation Of Execution Phase Of Apoptosis Protein Localization To Mitochondrion	Positive Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin Protein-containing Complex Binding Schwann Cell Migration Negative Regulation Of Glial Cell Migration Negative Regulation Of Schwann Cell Migration Hyaloid Vascular Plexus Regression Norepinephrine Uptake Dopamine Uptake Involved In Synaptic Transmission Catecholamine Catabolic Process Amine Binding Heterocyclic Compound Binding Monoamine Transmembrane Transporter Activity Norepinephrine:sodium Symporter Activity Dopamine Binding Norepinephrine Transport Dopamine Biosynthetic Process Dopamine:sodium Symporter Activity Adenohypophysis Development Dopamine Catabolic Process Flotillin Complex Lipid Droplet Fusion Catecholamine Uptake Dopamine Uptake Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Vasculogenesis Dopaminergic Synapse Prepulse Inhibition Anatomical Structure Regression COPI-coated Vesicle Lipid Transfer Activity Regulation Of Vasculogenesis Neurotransmitter Transmembrane Transporter Activity COPII Vesicle Coat Regulation Of Dopamine Metabolic Process Dopamine Transport Neurotransmitter Reuptake Catecholamine Biosynthetic Process COPII-coated Vesicle Cargo Loading Regulation Of Glial Cell Migration Plasma Lipoprotein Particle Assembly Execution Phase Of Apoptosis Phosphatidic Acid Binding Protein-lipid Complex Assembly Glial Cell Migration Protein Phosphatase 2A Binding Monoamine Transport Neurotransmitter Uptake Face Morphogenesis Response To Iron Ion Positive Regulation Of Multicellular Organism Growth
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