SNX5 and MIB1

Number of citations of the paper that reports this interaction (PMID 16857196)
12

Data Source:
HPRD (two hybrid)

		SNX5	MIB1
Gene Name		sorting nexin 5	mindbomb E3 ubiquitin protein ligase 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Phagocytic Cup Cytoplasmic Vesicle Membrane Retromer Complex Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Extrinsic Component Of Endosome Membrane Early Endosome Membrane Macropinocytic Cup Tubular Endosome	Cytoplasm Centrosome Cytosol Plasma Membrane Postsynaptic Density Cytoplasmic Vesicle
	Molecular Function	Protein Binding Dynactin Binding Phosphatidylinositol Binding	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Intracellular Protein Transport Pinocytosis Vesicle Organization Retrograde Transport, Endosome To Golgi	Blood Vessel Development In Utero Embryonic Development Somitogenesis Neural Tube Formation Heart Looping Endocytosis Notch Signaling Pathway Protein Ubiquitination Negative Regulation Of Neuron Differentiation Positive Regulation Of Endocytosis
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Signaling by NOTCH1 HD Domain Mutants in Cancer Constitutive Signaling by NOTCH1 HD Domain Mutants Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH NOTCH2 Activation and Transmission of Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Signaling by NOTCH2 Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Constitutive Signaling by NOTCH1 PEST Domain Mutants FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: APPBP2 CDC37 CLTC CLTCL1 DNAJB11 FANCA HGS HMOX2 ITSN1 MESDC2 MIB1 PFDN1 PRKRA SNX2	14 interactors: AZI2 BLM CEP131 DAB2 DAPK1 SNX5 TBK1 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2N UBE2U UBE2W
Entrez ID		27131	57534
HPRD ID		10439	06660
Ensembl ID		ENSG00000089006	ENSG00000101752
Uniprot IDs		Q6P5V6 Q9Y5X3	Q86YT6
PDB IDs		1SYS
Enriched GO Terms of Interacting Partners?		Cellular Protein Localization Intracellular Protein Transport Cellular Localization Protein Folding Endocytosis Protein Localization Establishment Of Localization In Cell Protein Transport Establishment Of Protein Localization Intracellular Transport Transport Vesicle-mediated Transport Developmental Process Negative Regulation Of Hyaluronan Biosynthetic Process Heme Oxidation Anatomical Structure Development Lamellipodium Morphogenesis	Protein Polyubiquitination Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Protein K48-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Protein Ubiquitination Protein Modification By Small Protein Conjugation TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Innate Immune Response MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Innate Immune Response Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein K11-linked Ubiquitination Dendritic Cell Proliferation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Immune System Process Cellular Response To Stress Protein Catabolic Process Response To Stress Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Immune Response-regulating Signaling Pathway Positive Regulation Of Immune System Process DNA Double-strand Break Processing Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Modification Process DNA Repair Pinocytosis Positive Regulation Of Immune Response Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Catabolic Process Type I Interferon Production Cellular Response To Oxygen Levels Cellular Response To Organic Substance Immune Response Regulation Of Immune System Process Defense Response Cellular Response To DNA Damage Stimulus Regulation Of Immune Response Cellular Response To Stimulus
Tagcloud ?		counteracted egf egfr endosomal endosomes escrt generating ilvs intraluminal laptm4b lysosomal machineries mves neutralizes oncoprotein p2 pip pipkigammai5 promoting ptdins recruiting sorting termination transform transmembrane ubiquitinated ubiquitination vesicles vesicular	atypical basal biotinylated cervical condylomas contribution counted counting dysplasia fields figures hpfs hpv immunohistochemically intensely layers make mfs mitotic parabasal probes progress proliferative rarely reach seen stained suprabasal undertaken
Tagcloud (Difference) ?		counteracted egf egfr endosomal endosomes escrt generating ilvs intraluminal laptm4b lysosomal machineries mves neutralizes oncoprotein p2 pip pipkigammai5 promoting ptdins recruiting sorting termination transform transmembrane ubiquitinated ubiquitination vesicles vesicular	atypical basal biotinylated cervical condylomas contribution counted counting dysplasia fields figures hpfs hpv immunohistochemically intensely layers make mfs mitotic parabasal probes progress proliferative rarely reach seen stained suprabasal undertaken
Tagcloud (Intersection) ?