SNX5 and PFDN1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		SNX5	PFDN1
Gene Name		sorting nexin 5	prefoldin subunit 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Phagocytic Cup Cytoplasmic Vesicle Membrane Retromer Complex Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Extrinsic Component Of Endosome Membrane Early Endosome Membrane Macropinocytic Cup Tubular Endosome	Prefoldin Complex
	Molecular Function	Protein Binding Dynactin Binding Phosphatidylinositol Binding	Sequence-specific DNA Binding Transcription Factor Activity Unfolded Protein Binding
	Biological Process	Intracellular Protein Transport Pinocytosis Vesicle Organization Retrograde Transport, Endosome To Golgi	Regulation Of Transcription, DNA-templated Protein Folding Cell Cycle Telencephalon Development Cerebellum Development Actin Cytoskeleton Organization B Cell Activation Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Protein folding Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Chaperonin-mediated protein folding
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: APPBP2 CDC37 CLTC CLTCL1 DNAJB11 FANCA HGS HMOX2 ITSN1 MESDC2 MIB1 PFDN1 PRKRA SNX2	54 interactors: ACTA1 ACTB ALB ASNA1 BRK1 CCDC85A CHGA DCTN1 DEFA1 DGCR14 EDRF1 EIF3C EIF4A2 EOMES EXT2 EZH2 FAM20C GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 KIAA1377 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 TUBA1A YEATS4 ZNF235
Entrez ID		27131	5201
HPRD ID		10439	05357
Ensembl ID		ENSG00000089006	ENSG00000113068
Uniprot IDs		Q6P5V6 Q9Y5X3	O60925
PDB IDs		1SYS
Enriched GO Terms of Interacting Partners?		Cellular Protein Localization Intracellular Protein Transport Cellular Localization Protein Folding Endocytosis Protein Localization Establishment Of Localization In Cell Protein Transport Establishment Of Protein Localization Intracellular Transport Transport Vesicle-mediated Transport Developmental Process Negative Regulation Of Hyaluronan Biosynthetic Process Heme Oxidation Anatomical Structure Development Lamellipodium Morphogenesis	Organelle Organization Cellular Localization Cellular Macromolecule Biosynthetic Process Cellular Component Assembly Macromolecule Biosynthetic Process Gene Expression Membrane Organization RNA Biosynthetic Process Cellular Protein Localization Establishment Of Protein Localization To Membrane Protein Localization Developmental Process Cerebral Cortex Regionalization Mitotic Cell Cycle Biosynthetic Process Cellular Process Cytoskeleton-dependent Intracellular Transport Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Metabolic Process Establishment Of Localization In Cell Anatomical Structure Development RNA Metabolic Process Organelle Localization 'de Novo' Posttranslational Protein Folding Intracellular Transport Cell Cycle Process 'de Novo' Protein Folding Regulation Of Metabolic Process Telencephalon Regionalization Regulation Of Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Protein Localization To Organelle Positive Regulation Of Cellular Metabolic Process Protein Localization To Membrane Vesicle Localization Regulation Of Cilium Assembly Multicellular Organismal Development Regulation Of Cellular Process Regulation Of Mitotic Cell Cycle Phase Transition Anatomical Structure Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Killing Of Cells Of Other Organism Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Phase Transition Anatomical Structure Formation Involved In Morphogenesis
Tagcloud ?		counteracted egf egfr endosomal endosomes escrt generating ilvs intraluminal laptm4b lysosomal machineries mves neutralizes oncoprotein p2 pip pipkigammai5 promoting ptdins recruiting sorting termination transform transmembrane ubiquitinated ubiquitination vesicles vesicular
Tagcloud (Difference) ?		counteracted egf egfr endosomal endosomes escrt generating ilvs intraluminal laptm4b lysosomal machineries mves neutralizes oncoprotein p2 pip pipkigammai5 promoting ptdins recruiting sorting termination transform transmembrane ubiquitinated ubiquitination vesicles vesicular
Tagcloud (Intersection) ?