SNX5 and PFDN1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		SNX5	PFDN1
Description		sorting nexin 5	prefoldin subunit 1
Image
GO Annotations	Cellular Component	Ruffle Phagocytic Cup Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Brush Border Cytoplasmic Side Of Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Retromer Complex Retromer, Tubulation Complex Cytoplasmic Vesicle Early Endosome Membrane Cell Projection Perinuclear Region Of Cytoplasm Macropinocytic Cup Tubular Endosome Cytoplasmic Side Of Early Endosome Membrane	Cytoplasm Prefoldin Complex Protein-containing Complex
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol-5-phosphate Binding D1 Dopamine Receptor Binding Dynactin Binding Phosphatidylinositol Binding Cadherin Binding Phosphatidylinositol-4-phosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding	Amyloid-beta Binding Protein Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Intracellular Protein Transport Endocytosis Pinocytosis Epidermal Growth Factor Catabolic Process Protein Transport Regulation Of Macroautophagy Retrograde Transport, Endosome To Golgi Negative Regulation Of Blood Pressure Positive Regulation Of DNA-templated Transcription Positive Regulation Of Insulin Receptor Signaling Pathway	Protein Folding Negative Regulation Of Amyloid Fibril Formation
Pathways		Golgi Associated Vesicle Biogenesis	Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Cholesterol, total ( 25961943) LDL cholesterol ( 24097068 25961943) LDL cholesterol levels ( 28334899 30698716 32203549) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Liver enzyme levels (alanine transaminase) ( 33972514) Low density lipoprotein cholesterol levels ( 33339817)	Alzheimer's disease ( 28183528) Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Reaction time ( 29844566)
Interacting Genes		21 interacting genes: APPBP2 AQP2 BANP CDC37 CLTC CLTCL1 DNAJB11 DSCR9 FANCA HGS HMOX2 ITSN1 LAMTOR5 MESD MIB1 NRP1 OGT PFDN1 PRKRA PSMB8 RIGI	55 interacting genes: ACTA1 ACTB ALB BRK1 CCDC85A CEBPA CEP126 CHGA DCTN1 DEFA1 DMAP1 EDRF1 EIF3C EIF4A2 EOMES ESS2 EXT2 EZH2 FAM20C GET3 GIT1 GPRASP1 HAP1 HIP1 HMGXB3 HOXD8 IFT140 IMMT INPP5K JADE1 KIAA0408 LRIF1 MED31 NDC80 NR2F1 PDE4DIP PDHB PFDN2 PLXNB2 PRKD2 PSME1 PTN RMI1 RPLP1 RPS28 SEC31A SKP2 SNX5 SPTBN4 SUMO3 SYNDIG1 TERT TTC38 YEATS4 ZNF235
Entrez ID		27131	5201
HPRD ID		10439	05357
Ensembl ID		ENSG00000089006	ENSG00000113068
Uniprot IDs		Q6P5V6 Q9Y5X3	O60925
PDB IDs		1SYS 5TGH 5TGI 5TGJ 5WY2 6N5X 6N5Y 6N5Z 8A1G 8ABQ 8AFZ	6NR8 6NR9 6NRB 6NRC 6NRD 7WU7
Enriched GO Terms of Interacting Partners?		Cytoplasmic Vesicle Membrane Clathrin Coat Of Trans-Golgi Network Vesicle Endocytosis Clathrin Complex Receptor-mediated Endocytosis Clathrin Light Chain Binding Sorting Endosome Protein Localization To Lysosome Import Into Cell Double-stranded RNA Binding Clathrin-coated Pit Protein Folding Intracellular Protein Localization Protein Localization To Vacuole Cytoplasm Endosomal Transport Clathrin-coated Endocytic Vesicle Unfolded Protein Binding Cytoplasmic Vesicle Low-density Lipoprotein Particle Receptor Binding Recycling Endosome Clathrin-dependent Endocytosis Protein Folding Chaperone Complex Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Protein Localization To Membrane Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Otic Placode Development Basal Dendrite Development	Positive Regulation Of Microtubule Nucleation Structural Constituent Of Cytoskeleton Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Microtubule Nucleation Nuclear Matrix Positive Regulation Of DNA Recombination NuA4 Histone Acetyltransferase Complex Regulation Of Cell Cycle Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Microtubule Polymerization Positive Regulation Of Double-strand Break Repair Intracellular Protein Localization Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Cytoskeleton Organization Regulation Of Supramolecular Fiber Organization Glutamate Receptor Binding Regulation Of Cellular Component Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?