ZBTB32 and PITX1

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		ZBTB32	PITX1
Gene Name		zinc finger and BTB domain containing 32	paired-like homeodomain 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome Nucleus Nucleoplasm	Nucleus Transcription Factor Complex Nucleolus Cytoplasm
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Transcription Factor Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cytokine Production DNA Repair Transcription From RNA Polymerase II Promoter Hemopoiesis T Cell Proliferation	Skeletal System Development Transcription, DNA-templated Anatomical Structure Morphogenesis Branchiomeric Skeletal Muscle Development Pituitary Gland Development Embryonic Hindlimb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Myoblast Fate Commitment Cartilage Development
Pathways		Fanconi Anemia pathway Regulation of the Fanconi anemia pathway
Drugs
Diseases
GWAS			Bulimia nervosa ( 23568457) Colorectal cancer ( 23263487) Height ( 20881960 23563607 18391951) Immune response to anthrax vaccine ( 22658931) Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		17 interactors: AR ATXN1 DAB1 ELF2 ERVK-6 FANCC GATA2 HOXD4 MLX MVP PITX1 PRKAB2 RBPMS RHOXF2 TXNIP ZBTB16 ZNF490	24 interactors: ALG13 C1orf94 CDX4 DVL3 EGR1 HGS IPO13 LZTS2 MAGED1 MGAT5B NEUROD1 NR5A1 PLSCR1 POU1F1 PRR20A RBPMS RFX6 RHOXF2 RNF31 SMARCA2 SPAG8 TRIM23 UPF2 ZBTB32
Entrez ID		27033	5307
HPRD ID		12055	03688
Ensembl ID		ENSG00000011590	ENSG00000069011
Uniprot IDs		Q9Y2Y4	P78337
PDB IDs		3M5B
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Embryonic Hindlimb Morphogenesis Pituitary Gland Development Ventral Spinal Cord Development Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Negative Regulation Of Integrin Biosynthetic Process Cellular Response To Tumor Cell Hindlimb Morphogenesis Nucleocytoplasmic Transport Nuclear Transport Cellular Metabolic Process Negative Regulation Of Signaling Regulation Of Cellular Process Developmental Process Involved In Reproduction Cerebellum Structural Organization	Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nuclear Transport Regulation Of Metabolic Process Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Pancreatic A Cell Differentiation Macromolecule Biosynthetic Process Regulation Of Signaling RNA Metabolic Process Regulation Of Signal Transduction Gene Expression Nucleocytoplasmic Transport Organ Development Negative Regulation Of JAK-STAT Cascade Enteroendocrine Cell Differentiation Negative Regulation Of Cell Proliferation Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Transcription, DNA-templated Cytoplasmic Transport Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process System Development Positive Regulation Of Kidney Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Multicellular Organismal Aging Negative Regulation Of Wnt Signaling Pathway Glandular Epithelial Cell Differentiation Negative Regulation Of Gene Expression Pancreatic Epsilon Cell Differentiation Positive Regulation Of Glomerular Metanephric Mesangial Cell Proliferation Pancreatic D Cell Differentiation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Canonical Wnt Signaling Pathway
Tagcloud ?			17beta 3x0 3x20 antide buserelin diarylpropionitrile dpn egr1 erb esr1 esr2 gnrh gnrhr gonadotroph lhb microinjected microinjections oestradiol oestrogenic orchestrated ovariectomised pituitaries ppt propyl pulsatile pulses pyrazole stimulations triol
Tagcloud (Difference) ?			17beta 3x0 3x20 antide buserelin diarylpropionitrile dpn egr1 erb esr1 esr2 gnrh gnrhr gonadotroph lhb microinjected microinjections oestradiol oestrogenic orchestrated ovariectomised pituitaries ppt propyl pulsatile pulses pyrazole stimulations triol
Tagcloud (Intersection) ?