ZBTB32 and HNRNPF

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB32	HNRNPF
Description		zinc finger and BTB domain containing 32	heterogeneous nuclear ribonucleoprotein F
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Plasma Membrane Membrane Synapse Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Nucleic Acid Binding RNA Binding Single-stranded RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process Negative Regulation Of DNA-templated Transcription	MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Splicing Regulation Of RNA Splicing
Pathways			FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278)	Antisaccade task score ( 31596458)
Interacting Genes		54 interacting genes: ANKS1A AR ATXN1 ATXN1L BLK BOLL CAMK2A CAMK2B CCDC102B CDKN2D CFAP206 DAB1 DAZAP2 E2F6 ELF2 ERVK-6 FANCC GATA2 HNRNPF HOXD4 KRTAP15-1 KRTAP19-5 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 MIEN1 MLX MVP MYO15B OXER1 PATZ1 PITX1 PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E PSMB1 RBPMS RBPMS2 RHOXF2 SHARPIN SPAG8 SPMIP9 TFAP2D TLX3 TNPO2 TXNIP VENTX WWOX ZBTB16 ZNF490	156 interacting genes: AKIRIN2 APOBEC1 ATN1 ATP23 AURKA BBS2 C10orf55 C1orf94 CCDC33 CPSF7 DSCAM DUX4 DZIP3 EIF4ENIF1 ERG FAM86C1P HNRNPA0 HNRNPH1 HNRNPH3 HNRNPM HNRNPUL1 HSFY1 HYPK IKZF3 INCA1 IQCE KLF1 KLF15 KPRP KRT75 KRTAP7-1 LASP1 LINC01554 LNX1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MRPL17 MSI1 NCBP1 NCBP2 NDRG1 NFKBID NUDT16L1 OGT PATZ1 PDLIM7 POLR2A PROP1 PRPF40A PRR22 PRR32 PRR34 RBFOX1 RBFOX2 RBM4 REL RNF10 RNF26 RUSC1 SF1 SF3B4 SLAIN1 SMUG1 SNRPC SORBS3 SPATA8 SUMO2 SUMO4 TENT5B TFG TGM2 TGM7 TLE5 TOE1 TRIB3 TRIM14 TXNL4A UNKL USP54 VAV2 VGLL1 VPS37C ZBTB32 ZNF581 ZNF689 ZNF764
Entrez ID		27033	3185
HPRD ID		12055	03023
Ensembl ID		ENSG00000011590	ENSG00000169813
Uniprot IDs		A0A0C4DGF1 Q9Y2Y4	P52597
PDB IDs		3M5B	2HGL 2HGM 2HGN 2KFY 2KG0 2KG1 3TFY
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity POZ Domain Binding Intermediate Filament Regulation Of Nucleobase-containing Compound Metabolic Process Keratinization Sequence-specific Double-stranded DNA Binding Calcium- And Calmodulin-dependent Protein Kinase Complex Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Nucleus Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process GABAergic Neuron Differentiation Male Germ Cell Nucleus Cytosol Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization Positive Regulation Of MRNA Metabolic Process Positive Regulation Of MRNA Catabolic Process RNA Destabilization Regulation Of Macromolecule Metabolic Process Regulation Of Translation Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of MRNA Stability Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Regulation Of RNA Stability Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Metabolic Process Negative Regulation Of Locomotion Regulation Of Angiogenesis Regulation Of Vasculature Development Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Protein Metabolic Process Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Endothelial Cell Migration Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Developmental Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Multicellular Organismal Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cytokine Production Regulation Of Cell Migration Involved In Sprouting Angiogenesis
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