ZBTB32 and ELF2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		ZBTB32	ELF2
Description		zinc finger and BTB domain containing 32	E74 like ETS transcription factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm Cytosol Nuclear Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process Negative Regulation Of DNA-templated Transcription	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription
Pathways			RUNX1 regulates transcription of genes involved in BCR signaling
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278)
Interacting Genes		54 interacting genes: ANKS1A AR ATXN1 ATXN1L BLK BOLL CAMK2A CAMK2B CCDC102B CDKN2D CFAP206 DAB1 DAZAP2 E2F6 ELF2 ERVK-6 FANCC GATA2 HNRNPF HOXD4 KRTAP15-1 KRTAP19-5 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 MIEN1 MLX MVP MYO15B OXER1 PATZ1 PITX1 PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E PSMB1 RBPMS RBPMS2 RHOXF2 SHARPIN SPAG8 SPMIP9 TFAP2D TLX3 TNPO2 TXNIP VENTX WWOX ZBTB16 ZNF490	5 interacting genes: APP EIF2AK2 LMO2 RUNX1 ZBTB32
Entrez ID		27033	1998
HPRD ID		12055	16856
Ensembl ID		ENSG00000011590	ENSG00000109381
Uniprot IDs		A0A0C4DGF1 Q9Y2Y4	B7Z720 Q15723
PDB IDs		3M5B
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity POZ Domain Binding Intermediate Filament Regulation Of Nucleobase-containing Compound Metabolic Process Keratinization Sequence-specific Double-stranded DNA Binding Calcium- And Calmodulin-dependent Protein Kinase Complex Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Nucleus Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process GABAergic Neuron Differentiation Male Germ Cell Nucleus Cytosol Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding	Regulation Of Cytokine Production Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of RNA Metabolic Process Positive Regulation Of Chemokine Production Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Cytokine Production Regulation Of Chemokine Production Regulation Of Response To Calcium Ion Regulation Of DNA-templated Transcription Amylin Binding Regulation Of RNA Biosynthetic Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Nucleobase-containing Compound Metabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Core-binding Factor Complex Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Hemopoiesis Positive Regulation Of Amyloid Fibril Formation Negative Regulation Of Macromolecule Biosynthetic Process Cellular Response To Norepinephrine Stimulus Negative Regulation Of Biosynthetic Process Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Cardiac Muscle Tissue Regeneration Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation DNA-binding Transcription Factor Binding Eukaryotic Translation Initiation Factor 2alpha Kinase Activity Regulation Of Gene Expression Regulation Of Spontaneous Synaptic Transmission Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II NMDA Selective Glutamate Receptor Signaling Pathway
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