ZBTB32 and MIEN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB32	MIEN1
Description		zinc finger and BTB domain containing 32	migration and invasion enhancer 1
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Cytoplasm Mitochondrion Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process Negative Regulation Of DNA-templated Transcription	Apoptotic Process Positive Regulation Of Cell Migration Negative Regulation Of Apoptotic Process Positive Regulation Of Filopodium Assembly
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278)	Asthma ( 29273806 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Systemic lupus erythematosus ( 28714469)
Interacting Genes		54 interacting genes: ANKS1A AR ATXN1 ATXN1L BLK BOLL CAMK2A CAMK2B CCDC102B CDKN2D CFAP206 DAB1 DAZAP2 E2F6 ELF2 ERVK-6 FANCC GATA2 HNRNPF HOXD4 KRTAP15-1 KRTAP19-5 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 MIEN1 MLX MVP MYO15B OXER1 PATZ1 PITX1 PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E PSMB1 RBPMS RBPMS2 RHOXF2 SHARPIN SPAG8 SPMIP9 TFAP2D TLX3 TNPO2 TXNIP VENTX WWOX ZBTB16 ZNF490	15 interacting genes: ARID5A DDIT4L GORASP2 HDAC7 HIVEP1 HLX HMGB1 HMGB2 NLGN3 POU6F2 REL RNF126 TRIP6 VENTX ZBTB32
Entrez ID		27033	84299
HPRD ID		12055	12681
Ensembl ID		ENSG00000011590	ENSG00000141741
Uniprot IDs		A0A0C4DGF1 Q9Y2Y4	J3KTI2 Q9BRT3
PDB IDs		3M5B	2LJK
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity POZ Domain Binding Intermediate Filament Regulation Of Nucleobase-containing Compound Metabolic Process Keratinization Sequence-specific Double-stranded DNA Binding Calcium- And Calmodulin-dependent Protein Kinase Complex Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process Nucleus Regulation Of Gene Expression Negative Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process GABAergic Neuron Differentiation Male Germ Cell Nucleus Cytosol Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Protein Binding	DNA Binding Regulation Of Transcription By RNA Polymerase II DNA Geometric Change Supercoiled DNA Binding Regulation Of Interferon-beta Production Regulation Of Nucleobase-containing Compound Metabolic Process DNA Topological Change Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process RAGE Receptor Binding Regulation Of Cytokine Production Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process T-helper 1 Cell Differentiation Regulation Of Non-canonical NF-kappaB Signal Transduction DNA Binding, Bending DNA Conformation Change Four-way Junction DNA Binding V(D)J Recombination Transcription Factor Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Regulation Of Type I Interferon Production Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Nuclear Thyroid Hormone Receptor Binding Negative Regulation Of Alpha-beta T Cell Differentiation Regulation Of Primary Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation Inflammatory Response To Antigenic Stimulus Chemoattractant Activity Condensed Chromosome Cellular Response To Lipopolysaccharide Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Sequence-specific DNA Binding T-helper Cell Differentiation Positive Regulation Of Interferon-beta Production DNA-binding Transcription Factor Binding Cellular Response To Molecule Of Bacterial Origin T Cell Differentiation Involved In Immune Response Positive Regulation Of Epithelial Cell Proliferation Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Somatic Cell DNA Recombination Positive Chemotaxis Transcription Corepressor Activity Negative Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process CD4-positive, Alpha-beta T Cell Differentiation Regulation Of Adaptive Immune Response
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