SH2B1 and SH2B2

  • Number of citations of the paper that reports this interaction (PMID 15767667)
  • 21
  • Data Source:
  • BioGRID (two hybrid, affinity chromatography technology)

SH2B1

SH2B2

Gene Name SH2B adaptor protein 1 SH2B adaptor protein 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 12 interactors: EGFR FGFR3 GRB2 IGF1R INSR IRS1 JAK2 KIAA0319 NTRK1 NTRK2 RHBG SH2B2 21 interactors: AKT1 ASB6 BTK CBL EPOR ERBB2 FYN GRB2 INSR JAK1 JAK2 JAK3 KIT LYN NTRK1 NTRK2 PDLIM7 SH2B1 SHC1 SORBS1 SYK
Entrez ID 25970 10603
HPRD ID 12336 16097
Ensembl ID ENSG00000178188
Uniprot IDs B3KNV5 B4DLN5 F5GXU7 Q9NRF2 O14492
PDB IDs 1Q2H
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actin  adapter  branching  depends  enhance  enhances  fact  filopoda  filopodia  filopodium  formation  hippocampal  initiation  insoluble  interacts  irsp53  isoform  localize  neurite  neurons  outgrowth  overexpressing  predominant  prerequisite  proline  regulate  rich  triton 
accordingly  adaptor  aps  assembling  called  counteract  dephosphorylation  dimerization  dimers  hetero  homo  hyperphagia  insects  irs1  irs2  leptin  obesity  protecting  protects  psm  sh2b1  sh2b1beta  sh2b3  transgenes  trka  tyrosyl 
Tagcloud (Difference) ?
actin  adapter  branching  depends  enhance  enhances  fact  filopoda  filopodia  filopodium  formation  hippocampal  initiation  insoluble  interacts  irsp53  isoform  localize  neurite  neurons  outgrowth  overexpressing  predominant  prerequisite  proline  regulate  rich  triton 
accordingly  adaptor  aps  assembling  called  counteract  dephosphorylation  dimerization  dimers  hetero  homo  hyperphagia  insects  irs1  irs2  leptin  obesity  protecting  protects  psm  sh2b3  transgenes  trka  tyrosyl 
Tagcloud (Intersection) ?
sh2b1  sh2b1beta