PVRL3 and MLLT4

Number of citations of the paper that reports this interaction (PMID 10744716)
52

Data Source:
HPRD (in vitro)

		PVRL3	MLLT4
Gene Name		poliovirus receptor-related 3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell-cell Adherens Junction Integral Component Of Membrane Apical Junction Complex Postsynaptic Membrane	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Cell-cell Adherens Junction Cell Junction Apical Part Of Cell
	Molecular Function	Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding	Protein Binding Protein C-terminus Binding Ras GTPase Binding Cell Adhesion Molecule Binding
	Biological Process	Lens Morphogenesis In Camera-type Eye Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Fertilization Single Organismal Cell-cell Adhesion Cell Junction Assembly Adherens Junction Organization Cell-cell Junction Organization Retina Morphogenesis In Camera-type Eye	Cell Adhesion Signal Transduction Cell-cell Signaling Positive Regulation Of Rap GTPase Activity Cell Junction Assembly Adherens Junction Organization Cell-cell Junction Organization Establishment Of Endothelial Intestinal Barrier
Pathways		Nectin/Necl trans heterodimerization Cell junction organization Cell-cell junction organization Adherens junctions interactions
Drugs
Diseases
GWAS			Metabolite levels (5-HIAA) ( 23319000)
Protein-Protein Interactions		13 interactors: KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 MLLT4 NOTCH2NL PARD3 PVR PVRL1 PVRL2 RGS20 TIGIT	37 interactors: BCR CTNNA1 EPHA7 EPHB2 EPHB3 EPHB6 F11R HRAS JAG1 LMO2 MRAS NRXN1 NRXN2 NRXN3 PFN1 PICK1 PVRL1 PVRL2 PVRL3 PVRL4 RALGDS RAP1A RAP1GAP RAP2A RIN1 RIT1 RIT2 RRAS RRAS2 SMAD2 SORBS1 SORBS2 SSX2IP TJP1 USP9X YWHAB YWHAG
Entrez ID		25945	4301
HPRD ID		08454	01164
Ensembl ID			ENSG00000130396
Uniprot IDs		Q9NQS3	P55196
PDB IDs		4FOM	1T2M 1XZ9 2AIN 2EXG
Enriched GO Terms of Interacting Partners?		Cell Junction Assembly Cell-cell Junction Organization Adherens Junction Organization Susceptibility To T Cell Mediated Cytotoxicity Viral Entry Into Host Cell Entry Into Host Cell Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Immune Response To Tumor Cell Interaction With Host Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Viral Life Cycle Response To Virus Cellular Component Assembly Coreceptor-mediated Virion Attachment To Host Cell Positive Regulation Of T Cell Mediated Cytotoxicity Cell Adhesion Regulation Of T Cell Mediated Cytotoxicity Locomotion Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Positive Regulation Of T Cell Mediated Immunity Regulation Of Leukocyte Mediated Cytotoxicity Viral Process Sperm Mitochondrion Organization Fusion Of Virus Membrane With Host Plasma Membrane Positive Regulation Of Adaptive Immune Response Response To Other Organism Response To Biotic Stimulus Positive Regulation Of Innate Immune Response Regulation Of Adaptive Immune Response Cell Development Apical Constriction Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Epithelial Cell Development Establishment Of Endothelial Intestinal Barrier Asymmetric Cell Division Cell Differentiation Cell Part Morphogenesis Enamel Mineralization Virion Attachment To Host Cell Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Regulation Of Innate Immune Response Adhesion Of Symbiont To Host Positive Regulation Of Myelination Tooth Mineralization	Signaling Cell Communication Enzyme Linked Receptor Protein Signaling Pathway Anatomical Structure Development Developmental Process Cell Development Cell Projection Organization Signal Transduction Nervous System Development Axon Development Cellular Response To Stimulus Generation Of Neurons Anatomical Structure Morphogenesis Neurogenesis Response To Stimulus Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Axon Guidance Axonogenesis Cell Part Morphogenesis System Development Cell Differentiation Neuron Differentiation Ras Protein Signal Transduction Multicellular Organismal Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Development Neuron Projection Development Neuron Projection Morphogenesis Locomotion Cell Projection Morphogenesis Regulation Of Signaling Cell Junction Assembly Cell Morphogenesis Involved In Differentiation Cell-cell Junction Organization Regulation Of Cellular Component Organization Cell Adhesion Chemotaxis Small GTPase Mediated Signal Transduction Movement Of Cell Or Subcellular Component Cell Morphogenesis Response To External Stimulus Adherens Junction Organization Cellular Component Assembly Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Signal Transduction Regulation Of Synapse Assembly Cellular Response To Organic Substance Response To Organic Substance Learning
Tagcloud ?			abl1 aff1 cbfb cryptic cytogenetics dek ell etv6 fifteen inv mllt1 mllt10 mllt3 mllt6 mrt multiplex myh11 nup214 p13 pbx1 q23 rara runx1 runx1t1 simplified tcf3 translocations zbtb16
Tagcloud (Difference) ?			abl1 aff1 cbfb cryptic cytogenetics dek ell etv6 fifteen inv mllt1 mllt10 mllt3 mllt6 mrt multiplex myh11 nup214 p13 pbx1 q23 rara runx1 runx1t1 simplified tcf3 translocations zbtb16
Tagcloud (Intersection) ?