NSL1 and CBX1

Number of citations of the paper that reports this interaction (PMID 20231385)
17

Data Source:
BioGRID (two hybrid)

		NSL1	CBX1
Gene Name		NSL1, MIS12 kinetochore complex component	chromobox homolog 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	MIS12/MIND Type Complex Nucleus Cytosol	Chromosome, Centromeric Region Chromatin Female Pronucleus Male Pronucleus Nucleoplasm Nuclear Heterochromatin Pericentric Heterochromatin Spindle Chromocenter
	Molecular Function	Protein Binding	Chromatin Binding Protein Binding Enzyme Binding Protein Homodimerization Activity Histone Methyltransferase Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Cell Division	Negative Regulation Of Transcription, DNA-templated
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS			Body mass index ( 20935630) Epilepsy (generalized) ( 22949513)
Protein-Protein Interactions		8 interactors: CBX1 CBX3 CBX5 DSN1 G6PC HSP90AA1 MIS12 SUGT1	29 interactors: ABI3BP ARL5A C11orf30 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EHMT2 HIST1H1E HIST1H3A HIST1H3C HIST3H3 KLF11 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN
Entrez ID		25936	10951
HPRD ID		12378	05149
Ensembl ID		ENSG00000117697	ENSG00000108468
Uniprot IDs		H7BY54 Q53FM2 Q96IY1	P83916 Q6IBN6
PDB IDs			2FMM 3F2U 3Q6S
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Nuclear Division Cell Cycle Process Cell Cycle Protein Import Into Mitochondrial Outer Membrane Organelle Organization Glucose-6-phosphate Transport Chromosome Segregation	DNA Methylation On Cytosine Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA Methylation Negative Regulation Of Cellular Metabolic Process DNA Modification Regulation Of Gene Expression, Epigenetic Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Regulation Of RNA Metabolic Process Chromatin Silencing Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification DNA Metabolic Process Gene Silencing Regulation Of Gene Expression DNA Methylation On Cytosine Within A CG Sequence C-5 Methylation Of Cytosine Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Methylation Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Organelle Organization Regulation Of Metabolic Process DNA Replication-dependent Nucleosome Assembly Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Silencing At RDNA RNA Biosynthetic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle S-adenosylmethioninamine Metabolic Process RNA Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Nucleosome Assembly DNA Methylation Involved In Embryo Development S-adenosylhomocysteine Metabolic Process Chromatin Assembly Cellular Macromolecule Biosynthetic Process Nucleosome Organization
Tagcloud ?			apobec3 ash2l cbx3 cbx5 cbx6 cbx7 chd3 chd4 dek dnmt3b hdac7 ino80e kat1 kdm1b kdm2b kdm5c kdm7 modifiers ncoa4 ontogenic ontogeny prmt1 prmt7 setd8 smarca2 smarca4 smarcb1 suv420h2 unveils
Tagcloud (Difference) ?			apobec3 ash2l cbx3 cbx5 cbx6 cbx7 chd3 chd4 dek dnmt3b hdac7 ino80e kat1 kdm1b kdm2b kdm5c kdm7 modifiers ncoa4 ontogenic ontogeny prmt1 prmt7 setd8 smarca2 smarca4 smarcb1 suv420h2 unveils
Tagcloud (Intersection) ?