NSL1 and SUGT1

Number of citations of the paper that reports this interaction (PMID 20404110)
16

Data Source:
BioGRID (pull down, affinity chromatography technology)

		NSL1	SUGT1
Gene Name		NSL1, MIS12 kinetochore complex component	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	MIS12/MIND Type Complex Nucleus Cytosol	Ubiquitin Ligase Complex Kinetochore Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Cell Cycle Chromosome Segregation Mitotic Nuclear Division Cell Division	Mitotic Nuclear Division Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Innate Immune Response
Pathways		Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase	The NLRP3 inflammasome Inflammasomes Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CBX1 CBX3 CBX5 DSN1 G6PC HSP90AA1 MIS12 SUGT1	15 interactors: BUB3 CSNK2A1 DSN1 HSP90AA1 HSPA4 MIS12 NR4A1 NSL1 PAXIP1 PLK1 PMF1 S100A6 S100B S100P SKP1
Entrez ID		25936	10910
HPRD ID		12378	09160
Ensembl ID		ENSG00000117697
Uniprot IDs		H7BY54 Q53FM2 Q96IY1	F5H5A9 Q9Y2Z0
PDB IDs			1RL1
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Nuclear Division Cell Cycle Process Cell Cycle Protein Import Into Mitochondrial Outer Membrane Organelle Organization Glucose-6-phosphate Transport Chromosome Segregation	Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Cycle Process Chromosome Segregation Cell Cycle Mitotic Nuclear Division Cell Division Mitotic Spindle Checkpoint Protein Import Into Mitochondrial Outer Membrane Negative Regulation Of Chromosome Segregation Organelle Organization Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Protein Ubiquitination Regulation Of Chromosome Organization Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Endothelial Cell Migration Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Chromosome Organization Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Chromosome Organization Chaperone-mediated Protein Complex Assembly Epithelial Cell Migration Epithelium Migration Regulation Of Proteolysis Negative Regulation Of Protein Catabolic Process G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Proteolysis Regulation Of Mitotic Nuclear Division Negative Regulation Of Protein Processing Positive Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Processing Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Ameboidal-type Cell Migration Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Regulation Of Proteasomal Protein Catabolic Process Axonogenesis Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition
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