CBX1 and ARL5A

Number of citations of the paper that reports this interaction (PMID 12414990)
7

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CBX1	ARL5A
Gene Name		chromobox homolog 1	ADP-ribosylation factor-like 5A
Image
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Female Pronucleus Male Pronucleus Nucleoplasm Nuclear Heterochromatin Pericentric Heterochromatin Spindle Chromocenter	Intracellular
	Molecular Function	Chromatin Binding Protein Binding Enzyme Binding Protein Homodimerization Activity Histone Methyltransferase Binding	GTP Binding
	Biological Process	Negative Regulation Of Transcription, DNA-templated	Small GTPase Mediated Signal Transduction
Pathways
Drugs
Diseases
GWAS		Body mass index ( 20935630) Epilepsy (generalized) ( 22949513)
Protein-Protein Interactions		29 interactors: ABI3BP ARL5A C11orf30 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EHMT2 HIST1H1E HIST1H3A HIST1H3C HIST3H3 KLF11 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN	6 interactors: APP CBX1 CBX3 CBX5 KPNA2 NMT1
Entrez ID		10951	26225
HPRD ID		05149	12343
Ensembl ID		ENSG00000108468
Uniprot IDs		P83916 Q6IBN6	Q9Y689
PDB IDs		2FMM 3F2U 3Q6S	1Z6Y 1ZJ6 2H16 2H17
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA Methylation Negative Regulation Of Cellular Metabolic Process DNA Modification Regulation Of Gene Expression, Epigenetic Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Regulation Of RNA Metabolic Process Chromatin Silencing Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification DNA Metabolic Process Gene Silencing Regulation Of Gene Expression DNA Methylation On Cytosine Within A CG Sequence C-5 Methylation Of Cytosine Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Methylation Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Organelle Organization Regulation Of Metabolic Process DNA Replication-dependent Nucleosome Assembly Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Silencing At RDNA RNA Biosynthetic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle S-adenosylmethioninamine Metabolic Process RNA Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Nucleosome Assembly DNA Methylation Involved In Embryo Development S-adenosylhomocysteine Metabolic Process Chromatin Assembly Cellular Macromolecule Biosynthetic Process Nucleosome Organization	Viral Process Synaptic Growth At Neuromuscular Junction N-terminal Peptidyl-glycine N-myristoylation Collateral Sprouting In Absence Of Injury Negative Regulation Of Cellular Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process N-terminal Protein Myristoylation Neuron Remodeling Protein Myristoylation Response To Light Stimulus Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Blood Coagulation Cellular Copper Ion Homeostasis Hemostasis Response To Radiation NLS-bearing Protein Import Into Nucleus Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle N-terminal Protein Amino Acid Modification Regulation Of Rhodopsin Mediated Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Rhodopsin Mediated Signaling Pathway Regulation Of Body Fluid Levels Mating Behavior Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Tagcloud ?		apobec3 ash2l cbx3 cbx5 cbx6 cbx7 chd3 chd4 dek dnmt3b hdac7 ino80e kat1 kdm1b kdm2b kdm5c kdm7 modifiers ncoa4 ontogenic ontogeny prmt1 prmt7 setd8 smarca2 smarca4 smarcb1 suv420h2 unveils	alteration anterograde apparatus arf arl5b arls cargo classic dispersed endosome endosomes gfp golgi hela localised mannose perturbation q70l rab retrograde rnai shiga t30n tagged tgn tgn38 toxin trans transport
Tagcloud (Difference) ?		apobec3 ash2l cbx3 cbx5 cbx6 cbx7 chd3 chd4 dek dnmt3b hdac7 ino80e kat1 kdm1b kdm2b kdm5c kdm7 modifiers ncoa4 ontogenic ontogeny prmt1 prmt7 setd8 smarca2 smarca4 smarcb1 suv420h2 unveils	alteration anterograde apparatus arf arl5b arls cargo classic dispersed endosome endosomes gfp golgi hela localised mannose perturbation q70l rab retrograde rnai shiga t30n tagged tgn tgn38 toxin trans transport
Tagcloud (Intersection) ?