CBX1 and ABI3BP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CBX1	ABI3BP
Gene Name		chromobox homolog 1	ABI family, member 3 (NESH) binding protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Female Pronucleus Male Pronucleus Nucleoplasm Nuclear Heterochromatin Pericentric Heterochromatin Spindle Chromocenter	Interstitial Matrix Extracellular Space Extracellular Matrix
	Molecular Function	Chromatin Binding Protein Binding Enzyme Binding Protein Homodimerization Activity Histone Methyltransferase Binding	Collagen Binding Heparin Binding
	Biological Process	Negative Regulation Of Transcription, DNA-templated	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways
Drugs
Diseases
GWAS		Body mass index ( 20935630) Epilepsy (generalized) ( 22949513)
Protein-Protein Interactions		29 interactors: ABI3BP ARL5A C11orf30 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EHMT2 HIST1H1E HIST1H3A HIST1H3C HIST3H3 KLF11 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN	6 interactors: ABI3 CBX1 FZD5 GOT1 GRB2 MBNL1
Entrez ID		10951	25890
HPRD ID		05149	09380
Ensembl ID		ENSG00000108468	ENSG00000154175
Uniprot IDs		P83916 Q6IBN6	D3YTG3 Q7Z7G0
PDB IDs		2FMM 3F2U 3Q6S
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA Methylation Negative Regulation Of Cellular Metabolic Process DNA Modification Regulation Of Gene Expression, Epigenetic Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Regulation Of RNA Metabolic Process Chromatin Silencing Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification DNA Metabolic Process Gene Silencing Regulation Of Gene Expression DNA Methylation On Cytosine Within A CG Sequence C-5 Methylation Of Cytosine Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Methylation Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Organelle Organization Regulation Of Metabolic Process DNA Replication-dependent Nucleosome Assembly Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Silencing At RDNA RNA Biosynthetic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle S-adenosylmethioninamine Metabolic Process RNA Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Nucleosome Assembly DNA Methylation Involved In Embryo Development S-adenosylhomocysteine Metabolic Process Chromatin Assembly Cellular Macromolecule Biosynthetic Process Nucleosome Organization	Branching Involved In Labyrinthine Layer Morphogenesis Labyrinthine Layer Morphogenesis Embryonic Placenta Morphogenesis Labyrinthine Layer Development In Utero Embryonic Development Embryonic Placenta Development Embryonic Morphogenesis Glutamate Catabolic Process To 2-oxoglutarate Glutamate Catabolic Process To Aspartate Aspartate Biosynthetic Process Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Regulation Of Chorionic Trophoblast Cell Proliferation Spemann Organizer Formation Fumarate Metabolic Process Glycerol Biosynthetic Process Aspartate Catabolic Process Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Placenta Development Cellular Response To Insulin Stimulus Morphogenesis Of A Branching Epithelium Glutamate Catabolic Process Morphogenesis Of A Branching Structure Aspartate Metabolic Process Chorionic Trophoblast Cell Differentiation Embryo Development Chorion Development Response To Insulin L-methionine Biosynthetic Process From Methylthioadenosine Cellular Response To Peptide Hormone Stimulus Regulation Of Tight Junction Assembly Cellular Response To Peptide L-methionine Salvage Post-embryonic Camera-type Eye Development Alternative MRNA Splicing, Via Spliceosome Dicarboxylic Acid Catabolic Process Fatty Acid Homeostasis 2-oxoglutarate Metabolic Process Oxaloacetate Metabolic Process Methionine Biosynthetic Process Anterior/posterior Axis Specification, Embryo Methionine Metabolic Process Response To Peptide Hormone Cellular Response To Organonitrogen Compound Sulfur Amino Acid Biosynthetic Process Response To Peptide Embryonic Organ Development Glutamate Metabolic Process Apoptotic Process Involved In Morphogenesis
Tagcloud ?		apobec3 ash2l cbx3 cbx5 cbx6 cbx7 chd3 chd4 dek dnmt3b hdac7 ino80e kat1 kdm1b kdm2b kdm5c kdm7 modifiers ncoa4 ontogenic ontogeny prmt1 prmt7 setd8 smarca2 smarca4 smarcb1 suv420h2 unveils	angioedema arachidonic associations aua bicc1 chinese clusters col24a1 entity fbxl7 galnac genome han hlf hypersensitivity intolerance nsaid nsaids rad51l rad51l1 reached rims1 scan spanish suffering suggestive t13 unrelated urticaria
Tagcloud (Difference) ?		apobec3 ash2l cbx3 cbx5 cbx6 cbx7 chd3 chd4 dek dnmt3b hdac7 ino80e kat1 kdm1b kdm2b kdm5c kdm7 modifiers ncoa4 ontogenic ontogeny prmt1 prmt7 setd8 smarca2 smarca4 smarcb1 suv420h2 unveils	angioedema arachidonic associations aua bicc1 chinese clusters col24a1 entity fbxl7 galnac genome han hlf hypersensitivity intolerance nsaid nsaids rad51l rad51l1 reached rims1 scan spanish suffering suggestive t13 unrelated urticaria
Tagcloud (Intersection) ?