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CBX1 and HIST1H3C
Number of citations of the paper that reports this interaction (PMID
11882902
)
149
Data Source:
HPRD
(in vitro)
CBX1
HIST1H3C
Gene Name
chromobox homolog 1
histone cluster 1, H3c
Image
Gene Ontology Annotations
Cellular Component
Chromosome, Centromeric Region
Chromatin
Female Pronucleus
Male Pronucleus
Nucleoplasm
Nuclear Heterochromatin
Pericentric Heterochromatin
Spindle
Chromocenter
Nuclear Chromosome
Nucleosome
Extracellular Region
Nucleus
Nucleoplasm
Membrane
Protein Complex
Extracellular Vesicular Exosome
Molecular Function
Chromatin Binding
Protein Binding
Enzyme Binding
Protein Homodimerization Activity
Histone Methyltransferase Binding
DNA Binding
Protein Binding
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Transcription, DNA-templated
Chromatin Silencing At RDNA
Chromatin Organization
DNA Replication-dependent Nucleosome Assembly
Blood Coagulation
Gene Expression
DNA Methylation On Cytosine
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Gene Silencing
Pathways
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
Mitotic Prophase
PKMTs methylate histone lysines
Regulatory RNA pathways
RNA Polymerase I Promoter Clearance
HDMs demethylate histones
Cellular Senescence
Signaling by Wnt
HATs acetylate histones
M Phase
Amyloids
NoRC negatively regulates rRNA expression
RNF mutants show enhanced WNT signaling and proliferation
XAV939 inhibits tankyrase, stabilizing AXIN
DNA methylation
Transcriptional regulation by small RNAs
Meiotic recombination
HDACs deacetylate histones
Chromatin organization
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling
RNA Polymerase I Transcription
formation of the beta-catenin:TCF transactivating complex
Epigenetic regulation of gene expression
Senescence-Associated Secretory Phenotype (SASP)
Negative epigenetic regulation of rRNA expression
Factors involved in megakaryocyte development and platelet production
PRC2 methylates histones and DNA
Cell Cycle, Mitotic
RMTs methylate histone arginines
Chromatin modifying enzymes
Oxidative Stress Induced Senescence
TCF dependent signaling in response to WNT
RNA Polymerase I Promoter Opening
SIRT1 negatively regulates rRNA Expression
Signaling by WNT in cancer
Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Body mass index (
20935630
)
Epilepsy (generalized) (
22949513
)
Protein-Protein Interactions
29 interactors:
ABI3BP
ARL5A
C11orf30
CBX3
CBX5
CHAF1A
DNMT1
DNMT3A
DNMT3B
EHMT2
HIST1H1E
HIST1H3A
HIST1H3C
HIST3H3
KLF11
LRIF1
NR2F6
NSL1
PCNA
PIM1
RB1
RPL12
SP100
SUV39H1
TRIM24
TRIM28
UCHL1
VHL
VTN
8 interactors:
ASF1A
ASF1B
CBX1
CENPA
DAXX
PHF1
TRIM24
UHRF1
Entrez ID
10951
8352
HPRD ID
05149
11906
Ensembl ID
ENSG00000108468
ENSG00000196532
Uniprot IDs
P83916
Q6IBN6
P68431
PDB IDs
2FMM
3F2U
3Q6S
1CS9
1CT6
1Q3L
2B2T
2B2U
2B2V
2B2W
2C1J
2C1N
2CV5
2KWJ
2KWK
2L75
2LBM
2M0O
2RI7
2UXN
3A1B
3AFA
3AVR
3AYW
3AZE
3AZF
3AZG
3AZH
3AZI
3AZJ
3AZK
3AZL
3AZM
3AZN
3B95
3KMT
3KQI
3LQI
3LQJ
3O34
3O35
3O37
3RIG
3RIY
3U4S
3U5N
3U5O
3U5P
3UEE
3UEF
3UIG
3UII
3UIK
3V43
3W96
3W97
3W98
3W99
3ZG6
3ZVY
4A0J
4A0N
4A7J
4BD3
4F4U
4F56
4FWF
4HON
4I51
Enriched GO Terms of Interacting Partners
?
DNA Methylation On Cytosine
Chromosome Organization
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Chromatin Organization
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
DNA Methylation
Negative Regulation Of Cellular Metabolic Process
DNA Modification
Regulation Of Gene Expression, Epigenetic
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of RNA Metabolic Process
Chromatin Silencing
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Modification
DNA Metabolic Process
Gene Silencing
Regulation Of Gene Expression
DNA Methylation On Cytosine Within A CG Sequence
C-5 Methylation Of Cytosine
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Methylation
Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Organelle Organization
Regulation Of Metabolic Process
DNA Replication-dependent Nucleosome Assembly
Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Silencing At RDNA
RNA Biosynthetic Process
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
S-adenosylmethioninamine Metabolic Process
RNA Metabolic Process
Transcription, DNA-templated
Cellular Metabolic Process
Nucleosome Assembly
DNA Methylation Involved In Embryo Development
S-adenosylhomocysteine Metabolic Process
Chromatin Assembly
Cellular Macromolecule Biosynthetic Process
Nucleosome Organization
Chromatin Modification
Chromatin Organization
Nucleosome Assembly
Chromatin Assembly
Nucleosome Organization
Chromatin Assembly Or Disassembly
Protein-DNA Complex Assembly
DNA Replication-independent Nucleosome Assembly
Chromosome Organization
DNA Packaging
DNA Conformation Change
DNA Replication-dependent Nucleosome Assembly
Transcription, DNA-templated
RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Cellular Macromolecular Complex Assembly
Regulation Of Gene Expression, Epigenetic
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Organelle Organization
RNA Metabolic Process
Gene Expression
Protein Complex Assembly
Negative Regulation Of Cellular Metabolic Process
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Macromolecule Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Stress
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Negative Regulation Of Histone H3-K27 Methylation
Chromatin Remodeling
Cellular Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Regulation Of Vitamin D Receptor Signaling Pathway
Cellular Component Assembly
Cellular Response To DNA Damage Stimulus
Negative Regulation Of Chromatin Silencing
Positive Regulation Of Metabolic Process
Tagcloud
?
apobec3
ash2l
cbx3
cbx5
cbx6
cbx7
chd3
chd4
dek
dnmt3b
hdac7
ino80e
kat1
kdm1b
kdm2b
kdm5c
kdm7
modifiers
ncoa4
ontogenic
ontogeny
prmt1
prmt7
setd8
smarca2
smarca4
smarcb1
suv420h2
unveils
Tagcloud (Difference)
?
apobec3
ash2l
cbx3
cbx5
cbx6
cbx7
chd3
chd4
dek
dnmt3b
hdac7
ino80e
kat1
kdm1b
kdm2b
kdm5c
kdm7
modifiers
ncoa4
ontogenic
ontogeny
prmt1
prmt7
setd8
smarca2
smarca4
smarcb1
suv420h2
unveils
Tagcloud (Intersection)
?