CBX1 and C11orf30

Number of citations of the paper that reports this interaction (PMID 14651845)
74

Data Source:
HPRD (in vivo, in vitro)

		CBX1	C11orf30
Gene Name		chromobox homolog 1	chromosome 11 open reading frame 30
Image
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Female Pronucleus Male Pronucleus Nucleoplasm Nuclear Heterochromatin Pericentric Heterochromatin Spindle Chromocenter	Nucleoplasm
	Molecular Function	Chromatin Binding Protein Binding Enzyme Binding Protein Homodimerization Activity Histone Methyltransferase Binding	Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription, DNA-templated	DNA Repair Transcription, DNA-templated Regulation Of Transcription, DNA-templated Chromatin Modification
Pathways
Drugs
Diseases
GWAS		Body mass index ( 20935630) Epilepsy (generalized) ( 22949513)	Allergic rhinitis ( 22036096) Atopic dermatitis ( 23042114 19349984) Crohn's disease ( 18587394 21102463) IgE grass sensitization ( 22036096)
Protein-Protein Interactions		29 interactors: ABI3BP ARL5A C11orf30 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EHMT2 HIST1H1E HIST1H3A HIST1H3C HIST3H3 KLF11 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN	6 interactors: BRCA2 CBX1 DDIT3 HIST3H3 ZMYND11 ZNF646
Entrez ID		10951	56946
HPRD ID		05149	10544
Ensembl ID		ENSG00000108468	ENSG00000158636
Uniprot IDs		P83916 Q6IBN6	B7ZKU0 B7ZKU2 E9PMC9 Q17RM7 Q7Z589
PDB IDs		2FMM 3F2U 3Q6S	1UTU 1UZ3 2FMM
Enriched GO Terms of Interacting Partners?		DNA Methylation On Cytosine Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process DNA Methylation Negative Regulation Of Cellular Metabolic Process DNA Modification Regulation Of Gene Expression, Epigenetic Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Regulation Of RNA Metabolic Process Chromatin Silencing Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification DNA Metabolic Process Gene Silencing Regulation Of Gene Expression DNA Methylation On Cytosine Within A CG Sequence C-5 Methylation Of Cytosine Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Methylation Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Organelle Organization Regulation Of Metabolic Process DNA Replication-dependent Nucleosome Assembly Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Silencing At RDNA RNA Biosynthetic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle S-adenosylmethioninamine Metabolic Process RNA Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Nucleosome Assembly DNA Methylation Involved In Embryo Development S-adenosylhomocysteine Metabolic Process Chromatin Assembly Cellular Macromolecule Biosynthetic Process Nucleosome Organization	Negative Regulation Of Biosynthetic Process Negative Regulation Of Determination Of Dorsal Identity Regulation Of Transcription Involved In Anterior/posterior Axis Specification Negative Regulation Of Cellular Metabolic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Mammary Gland Epithelial Cell Proliferation Chromosome Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Replication Fork Protection Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process ER Overload Response Response To UV-C Negative Regulation Of Gene Expression Apoptotic Signaling Pathway MRNA Transcription From RNA Polymerase II Promoter DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Cell Cycle Nitrogen Compound Metabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Blood Vessel Maturation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress MRNA Transcription Regulation Of Mammary Gland Epithelial Cell Proliferation Negative Regulation Of Myoblast Differentiation Inner Cell Mass Cell Proliferation Cellular Macromolecule Biosynthetic Process Oocyte Maturation Macromolecule Biosynthetic Process Blastocyst Growth Male Meiosis I Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Interleukin-8 Production Response To X-ray Negative Regulation Of JNK Cascade Centrosome Duplication Chromatin Modification Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Stress-activated MAPK Cascade
Tagcloud ?		apobec3 ash2l cbx3 cbx5 cbx6 cbx7 chd3 chd4 dek dnmt3b hdac7 ino80e kat1 kdm1b kdm2b kdm5c kdm7 modifiers ncoa4 ontogenic ontogeny prmt1 prmt7 setd8 smarca2 smarca4 smarcb1 suv420h2 unveils	adam9 aurka birc5 ccne1 cdc6 cdh1 cpd devoid emsy esr1 fgfr1 holland ikbkb mapt mathematical meaning med1 microdissection mlpa mrc mtdh multiplex numerical p078 prdm14 qiagen salsa top2a traf4
Tagcloud (Difference) ?		apobec3 ash2l cbx3 cbx5 cbx6 cbx7 chd3 chd4 dek dnmt3b hdac7 ino80e kat1 kdm1b kdm2b kdm5c kdm7 modifiers ncoa4 ontogenic ontogeny prmt1 prmt7 setd8 smarca2 smarca4 smarcb1 suv420h2 unveils	adam9 aurka birc5 ccne1 cdc6 cdh1 cpd devoid emsy esr1 fgfr1 holland ikbkb mapt mathematical meaning med1 microdissection mlpa mrc mtdh multiplex numerical p078 prdm14 qiagen salsa top2a traf4
Tagcloud (Intersection) ?