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CBX1
Gene Name
chromobox homolog 1
Image
Gene Ontology Annotations
Cellular Component
Chromosome, Centromeric Region
Chromatin
Female Pronucleus
Male Pronucleus
Nucleoplasm
Nuclear Heterochromatin
Pericentric Heterochromatin
Spindle
Chromocenter
Molecular Function
Chromatin Binding
Protein Binding
Enzyme Binding
Protein Homodimerization Activity
Histone Methyltransferase Binding
Biological Process
Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Body mass index (
20935630
)
Epilepsy (generalized) (
22949513
)
Protein-protein Interactions
29 interactors:
ABI3BP
ARL5A
C11orf30
CBX3
CBX5
CHAF1A
DNMT1
DNMT3A
DNMT3B
EHMT2
HIST1H1E
HIST1H3A
HIST1H3C
HIST3H3
KLF11
LRIF1
NR2F6
NSL1
PCNA
PIM1
RB1
RPL12
SP100
SUV39H1
TRIM24
TRIM28
UCHL1
VHL
VTN
Entrez ID
10951
HPRD ID
05149
Ensembl ID
ENSG00000108468
Uniprot IDs
P83916
Q6IBN6
PDB IDs
2FMM
3F2U
3Q6S
Enriched GO Terms of Interacting Partners
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DNA Methylation On Cytosine
Chromosome Organization
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Chromatin Organization
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
DNA Methylation
Negative Regulation Of Cellular Metabolic Process
DNA Modification
Regulation Of Gene Expression, Epigenetic
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of RNA Metabolic Process
Chromatin Silencing
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Modification
DNA Metabolic Process
Gene Silencing
Regulation Of Gene Expression
DNA Methylation On Cytosine Within A CG Sequence
C-5 Methylation Of Cytosine
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Methylation
Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Organelle Organization
Regulation Of Metabolic Process
DNA Replication-dependent Nucleosome Assembly
Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Silencing At RDNA
RNA Biosynthetic Process
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
S-adenosylmethioninamine Metabolic Process
RNA Metabolic Process
Transcription, DNA-templated
Cellular Metabolic Process
Nucleosome Assembly
DNA Methylation Involved In Embryo Development
S-adenosylhomocysteine Metabolic Process
Chromatin Assembly
Cellular Macromolecule Biosynthetic Process
Nucleosome Organization
Tagcloud
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chd4
dek
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hdac7
ino80e
kat1
kdm1b
kdm2b
kdm5c
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modifiers
ncoa4
ontogenic
ontogeny
prmt1
prmt7
setd8
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smarca4
smarcb1
suv420h2
unveils