NCR3 and BAG6

Number of citations of the paper that reports this interaction (PMID 24133212)
1

Data Source:
BioGRID (unspecified method, pull down)

		NCR3	BAG6
Gene Name		natural cytotoxicity triggering receptor 3	BCL2-associated athanogene 6
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle BAT3 Complex
	Molecular Function		Protein Binding Hsp70 Protein Binding Polyubiquitin Binding Ubiquitin Protein Ligase Binding Ribosome Binding Proteasome Binding
	Biological Process	Inflammatory Response Immune Response Cell Recognition Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity	Kidney Development Immune System Process Ubiquitin-dependent Protein Catabolic Process Transport Synaptonemal Complex Assembly Spermatogenesis Brain Development Embryo Development Chromatin Modification Internal Peptidyl-lysine Acetylation Cell Differentiation Lung Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Proliferation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Apoptotic Process Negative Regulation Of Proteolysis Protein Stabilization Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways
Drugs
Diseases
GWAS		Pulmonary function ( 21946350) Pulmonary function (interaction) ( 23284291) Weight ( 19079260)	Schizophrenia ( 23894747)
Protein-Protein Interactions		3 interactors: BAG6 CD247 CD59	102 interactors: ACVR1B AMFR ANXA7 ARPC3 ATN1 ATXN2 B2M C1QA CD93 CDK16 CDK4 CDK5 CDKN1A CHN2 CLU CSNK2B CSTF2 CTCFL CTSB CTSE CTSL CXCL8 DNAJB11 DPT EDN1 EFEMP1 EFEMP2 EP300 FAM173A FAM46A FAM9B FAS FKBP2 FZD4 GADD45A GLRA2 GSK3B HSPA13 HSPA8 ICK IGF2 IGFBP5 IKBKAP IMMT IQCG KLHL12 LBP LPPR3 MAPK6 MAVS MEST MYDGF NBL1 NCR3 NDUFA6 NDUFB11 NOMO1 NPY NR1H2 PELP1 PIN1 PLA2G2A PLK1 POLR2J PPAP2C PRMT2 PRNP PRPF40A PTH PTN PTPN12 RAB8A RAC1 RCC1 RCN2 REG1B RNF126 S100A4 SDC2 SEC61A1 SEC61B SERPING1 SERPINH1 SETDB1 SGTA SMN1 SPP1 SRGN STX5 TAC1 TDGF1 TFCP2 TK1 TOMM20 TP63 TTR UBL4A UBL7 UBQLN4 VAMP2 XRN1 ZFYVE9
Entrez ID		259197	7917
HPRD ID		11384	00808
Ensembl ID		ENSG00000204475	ENSG00000204463
Uniprot IDs		O14931 Q05D23	P46379
PDB IDs		3NOI 3PV6	1WX9 4DWF 4EEW
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Activation Of Membrane Attack Complex Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of T Cell Activation Positive Regulation Of Cell Activation Negative Regulation Of Protein Processing Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Immune System Process Tail-anchored Membrane Protein Insertion Into ER Membrane Regulation Of Lymphocyte Activation Regulation Of Protein Processing Protein Insertion Into ER Membrane Regulation Of Cell Activation Negative Regulation Of Complement Activation Regulation Of Cell Adhesion Protein Insertion Into Membrane Synaptonemal Complex Assembly Synaptonemal Complex Organization Regulation Of Defense Response To Virus By Virus Response To Stress Innate Immune Response Regulation Of Complement Activation Regulation Of Immune Response Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Protein Metabolic Process Positive Regulation Of Immune System Process Negative Regulation Of Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Endoplasmic Reticulum Organization Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Humoral Immune Response Synapsis Homologous Chromosome Segregation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Immune Response Regulation Of Immune System Process Regulation Of Acute Inflammatory Response Defense Response Negative Regulation Of Cellular Protein Catabolic Process T Cell Costimulation Meiotic Chromosome Segregation Regulation Of Defense Response To Virus Positive Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Signal Transduction	Response To Organic Substance Response To Stress Response To Stimulus Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Signaling Cell Communication Positive Regulation Of Protein Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Protein Phosphorylation Immune Response Regulation Of Immune System Process Regulation Of Protein Phosphorylation Cellular Response To Stimulus Defense Response Regulation Of Signaling Anatomical Structure Development Positive Regulation Of Cellular Protein Metabolic Process Innate Immune Response Regulation Of Cell Cycle Response To External Stimulus Signal Transduction Developmental Process Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Regulation Of Cellular Component Organization Positive Regulation Of Immune System Process Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Cell Development System Development Regulation Of Phosphorylation Regulation Of Signal Transduction Response To Hormone Immune System Process Response To Lipid Regulation Of Protein Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Protein Metabolic Process Regulation Of Cellular Process Cellular Process Regulation Of Catalytic Activity Response To Abiotic Stimulus Positive Regulation Of Metabolic Process Regulation Of Cell Motility Apoptotic Signaling Pathway Multicellular Organismal Development Positive Regulation Of Signal Transduction
Tagcloud ?		bring btg1 cyr61 dcs e7 epha1 hla idc idcs igfbp3 igsf6 il8 kpna7 mdc mdcs mrps11 nfkb1a nfkbia padre pgf pidc pulsed pulsing rad21 sema6a srgn trem2 tubal3 txnrd1	biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides sgta solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Difference) ?		bring btg1 cyr61 dcs e7 epha1 hla idc idcs igfbp3 igsf6 il8 kpna7 mdc mdcs mrps11 nfkb1a nfkbia padre pgf pidc pulsed pulsing rad21 sema6a srgn trem2 tubal3 txnrd1	biochemically biophysical calorimetry compete connecting decided dimerisation glutamine haddock helices hydrophobic isothermal itc microscale mst nt paths perturbation resides sgta solve tetratricopeptide thermophoresis titration tpr trc35 trimeric ubl ubl4a
Tagcloud (Intersection) ?