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NCR3
Description
natural cytotoxicity triggering receptor 3
Image
GO Annotations
Cellular Component
Plasma Membrane
Membrane
Molecular Function
Protein Binding
Identical Protein Binding
Immune Receptor Activity
Biological Process
Immune System Process
Immune Response-activating Cell Surface Receptor Signaling Pathway
Inflammatory Response
Immune Response
Cell Recognition
Natural Killer Cell Activation
Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity
NK T Cell Activation
Pathways
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS
A body shape index (
34021172
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Appendicular lean mass (
33097823
)
Asthma (
31619474
)
Asthma (childhood onset) (
31619474
)
Asthma and major depressive disorder (
31619474
)
Autism spectrum disorder or schizophrenia (
28540026
)
Hip circumference adjusted for BMI (
34021172
)
Hypertension (
30226566
)
Inflammatory bowel disease (
28067908
)
Lung function (FEV1) (
28166213
)
Lung function (FEV1/FVC) (
28166213
)
Malaria (
31844061
)
Pulmonary function (
21946350
)
Pulmonary function (smoking interaction) (
23284291
)
Rosacea symptom severity (
29771307
)
Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) (
26651848
)
Takayasu arteritis (
25604533
)
Type 1 diabetes and autoimmune thyroid diseases (
25936594
)
Ulcerative colitis (
28067908
)
Waist circumference adjusted for body mass index (
34021172
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Weight (
19079260
)
Interacting Genes
5 interacting genes:
BAG6
CD247
CD59
FAM209A
FCER1G
Entrez ID
259197
HPRD ID
11384
Ensembl ID
ENSG00000204475
Uniprot IDs
O14931
Q05D23
PDB IDs
3NOI
3PV6
6YJP
9FWW
Enriched GO Terms of Interacting Partners
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Fc-gamma Receptor III Complex
Activation Of Immune Response
Positive Regulation Of Immune Response
Plasma Membrane Protein Complex
Positive Regulation Of Protein Localization To Cell Surface
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Immune Response
Fc-gamma Receptor Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Regulation Of Protein Localization To Cell Surface
T Cell Activation
Positive Regulation Of Immune System Process
Immune Response-activating Signaling Pathway
Fc Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Tertiary Granule Membrane
Lymphocyte Activation
IgE Receptor Activity
Leukocyte Activation
Alpha-beta T Cell Activation
Regulation Of Immune System Process
Cell Activation
Positive Regulation Of Type I Hypersensitivity
Fc-epsilon Receptor I Complex
Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control
Immune System Process
Cell Surface Receptor Signaling Pathway
Gamma-delta T Cell Receptor Complex
Negative Regulation Of Activation Of Membrane Attack Complex
Negative Regulation Of Mast Cell Apoptotic Process
Serotonin Secretion By Platelet
Positive Regulation Of Type III Hypersensitivity
BAT3 Complex
Mast Cell Apoptotic Process
Serotonin Secretion
Positive Regulation Of Type IIa Hypersensitivity
Maintenance Of Unfolded Protein
Negative Regulation Of Complement-dependent Cytotoxicity
Positive Regulation Of Mast Cell Cytokine Production
IgE Binding
Regulation Of Mast Cell Apoptotic Process
Transmembrane Signaling Receptor Activity
Alpha-beta T Cell Receptor Complex
Complement Binding
Positive Regulation Of Hypersensitivity
Interleukin-3-mediated Signaling Pathway
Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus
Mast Cell Activation
Internal Peptidyl-lysine Acetylation
NK T Cell Activation
Tagcloud
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