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POLR1A and RRN3
Number of citations of the paper that reports this interaction (PMID
11250903
)
52
Data Source:
HPRD
(in vivo, in vitro)
POLR1A
RRN3
Gene Name
polymerase (RNA) I polypeptide A, 194kDa
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
DNA-directed RNA Polymerase I Complex
Cytoplasm
Nucleus
Nucleoplasm
Nucleolus
Molecular Function
RNA Polymerase I Activity
DNA Binding
Protein Binding
Zinc Ion Binding
RNA Polymerase Binding
Biological Process
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Gene Expression
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
In Utero Embryonic Development
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Nucleolus Organization
Cytoplasm Organization
Cell Proliferation
Gene Expression
Ribosome Biogenesis
Positive Regulation Of Transcription, DNA-templated
Homeostasis Of Number Of Cells
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Regulation Of DNA-templated Transcription, Initiation
Pathways
NoRC negatively regulates rRNA expression
RNA Polymerase I Chain Elongation
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription
RNA Polymerase I Transcription Termination
RNA Polymerase I Promoter Escape
RNA Polymerase I Promoter Clearance
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS
Protein-Protein Interactions
7 interactors:
ANP32B
NFKBIB
NOLC1
POLR1E
REL
RRN3
TCF4
10 interactors:
CCNE1
CDK2
EIF3L
MYO1C
POLR1A
POLR1B
PPP2R2A
TAF1A
TAF1B
TAF1C
Entrez ID
25885
54700
HPRD ID
10161
12004
Ensembl ID
ENSG00000068654
ENSG00000085721
Uniprot IDs
O95602
Q9H6T2
F5H148
Q9NYV6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Nucleolus Organization
Positive Regulation Of Protein Export From Nucleus
Protein-DNA Complex Assembly
DNA-templated Transcription, Initiation
Transcription Initiation From RNA Polymerase I Promoter
Regulation Of Protein Export From Nucleus
Transcription From RNA Polymerase I Promoter
RNA Metabolic Process
Positive Regulation Of Cytokine Production
Transcription, DNA-templated
RNA Biosynthetic Process
Positive Regulation Of Type I Interferon Production
Nucleobase-containing Compound Metabolic Process
Regulation Of Cytokine Production
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Type I Interferon Production
Positive Regulation Of Nucleocytoplasmic Transport
Cellular Nitrogen Compound Metabolic Process
Nucleus Organization
Regulation Of Cell Death
RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Catenin Import Into Nucleus
Cellular Macromolecular Complex Assembly
Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Nitrogen Compound Metabolic Process
Positive Regulation Of Intracellular Protein Transport
Gene Expression
Maintenance Of DNA Repeat Elements
Innate Immune Response
Cellular Macromolecule Biosynthetic Process
Ribosome Biogenesis
Macromolecule Biosynthetic Process
Regulation Of Nucleocytoplasmic Transport
Embryonic Hindgut Morphogenesis
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
Embryonic Genitalia Morphogenesis
Positive Regulation Of Intracellular Transport
Negative Regulation Of Cell Death
Cytoplasm Organization
Myoblast Fate Commitment
Negative Regulation Of Apoptotic Signaling Pathway
Regulation Of Intracellular Protein Transport
Secretory Granule Localization
Hindgut Morphogenesis
Insulin Metabolic Process
Positive Regulation Of Interleukin-12 Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription From RNA Polymerase I Promoter
DNA-templated Transcription, Termination
Negative Regulation Of Gene Expression, Epigenetic
DNA-templated Transcription, Elongation
Regulation Of Gene Expression, Epigenetic
DNA-templated Transcription, Initiation
Chromatin Silencing At RDNA
Chromatin Silencing
Gene Silencing
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
RRNA Transcription
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Gene Expression
Cellular Nitrogen Compound Metabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Metabolic Process
Nucleologenesis
RNA Metabolic Process
RNA Polymerase I Transcriptional Preinitiation Complex Assembly At The Promoter For The Nuclear Large RRNA Transcript
G2/M Transition Of Mitotic Cell Cycle
Nucleus Organization
Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter
Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway
Transcription, DNA-templated
RNA Biosynthetic Process
Positive Regulation Of DNA-dependent DNA Replication Initiation
G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway
Mitotic Cell Cycle Process
Post-embryonic Hemopoiesis
Nucleolus Organization
Cellular Metabolic Process
Mitotic Cell Cycle
Regulation Of DNA-dependent DNA Replication Initiation
Mitotic Nuclear Envelope Reassembly
Glomerular Visceral Epithelial Cell Development
Regulation Of Tight Junction Assembly
Metabolic Process
Nuclear Envelope Reassembly
Tagcloud
?
architecture
assemble
assembles
assembly
binds
biochemical
cf
comprising
conserved
cross
extend
insight
interconnected
linking
network
orthologous
pol
preinitiation
providing
rrn11
rrn6
rrn7
sl1
subunits
tata
tbp
tfiib
upstream
validated
Tagcloud (Difference)
?
architecture
assemble
assembles
assembly
binds
biochemical
cf
comprising
conserved
cross
extend
insight
interconnected
linking
network
orthologous
pol
preinitiation
providing
rrn11
rrn6
rrn7
sl1
subunits
tata
tbp
tfiib
upstream
validated
Tagcloud (Intersection)
?