BRMS1L and EXOC5

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		BRMS1L	EXOC5
Gene Name		breast cancer metastasis-suppressor 1-like	exocyst complex component 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Sin3-type Complex	Cytoplasm Cytosol
	Molecular Function	Histone Deacetylase Activity Histone Deacetylase Binding	Ral GTPase Binding Protein N-terminus Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Histone Deacetylation Regulation Of Growth	Exocytosis Post-Golgi Vesicle-mediated Transport Organelle Organization Protein Transport Cellular Protein Metabolic Process Vesicle Docking Membrane Organization
Pathways			Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS			Alcohol consumption ( 23743675)
Protein-Protein Interactions		15 interactors: ACTN2 AMOTL2 BRMS1 CCDC67 EXOC5 HDAC1 HDAC2 ING1 LINC00152 MID2 RBBP4 RBBP7 RBP1 SAP30 SIN3A	30 interactors: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C9orf9 CCDC102B CCDC67 CDH2 EDRF1 ENO2 FRMD6 HDDC3 ICA1 KXD1 MAGEA6 OAS1 PRKCG PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 TBX21 TNPO2 TTC23L TXLNB TXNL4A
Entrez ID		84312	10640
HPRD ID		16564	07258
Ensembl ID		ENSG00000100916	ENSG00000070367
Uniprot IDs		B2RD65 Q5PSV4	F8W9B8 O00471 Q8IW24
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic Chromatin Organization Chromatin Modification Chromosome Organization Negative Regulation Of Gene Expression Histone Deacetylation Protein Deacetylation Organelle Organization Negative Regulation Of RNA Biosynthetic Process ATP-dependent Chromatin Remodeling Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Histone H3-K9 Modification Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Histone Modification Regulation Of RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Remodeling Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Fungiform Papilla Formation Fungiform Papilla Morphogenesis Transcription, DNA-templated Positive Regulation Of Receptor Biosynthetic Process Fungiform Papilla Development Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Eyelid Development In Camera-type Eye Hair Follicle Placode Formation Regulation Of Transcription From RNA Polymerase II Promoter Tongue Morphogenesis Regulation Of Receptor Biosynthetic Process Histone H4 Deacetylation Regulation Of Gene Expression Negative Regulation Of Viral Transcription Blood Coagulation Hemostasis CENP-A Containing Nucleosome Assembly Histone H3 Deacetylation Regulation Of Cell Death RNA Metabolic Process Tongue Development Histone Exchange DNA Replication-independent Nucleosome Assembly Epithelial Cell Differentiation Gene Expression Regulation Of Body Fluid Levels	Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport Regulation Of Endocytosis Ras Protein Signal Transduction Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Positive Regulation Of Cellular Component Biogenesis Small GTPase Mediated Signal Transduction Intracellular Signal Transduction Actin Filament-based Process Regulation Of Rac Protein Signal Transduction Positive Regulation Of Protein Complex Assembly Regulation Of Actin Filament-based Process Regulation Of Actin Filament Polymerization Positive Regulation Of Mismatch Repair Phagolysosome Assembly Involved In Apoptotic Cell Clearance Regulation Of Filopodium Assembly Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Myeloid Dendritic Cell Activation Involved In Immune Response Regulation Of Mismatch Repair Positive Regulation Of Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Negative Regulation Of MRNA 3'-end Processing Epithelial Cell Differentiation Cellular Protein Localization Response To Virus Cellular Response To Organic Substance
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