PTF1A and RPGRIP1

Number of citations of the paper that reports this interaction (PMID 25355311)
0

Data Source:
BioGRID (two hybrid)

		PTF1A	RPGRIP1
Gene Name		pancreas specific transcription factor, 1a	retinitis pigmentosa GTPase regulator interacting protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Cytoplasm	Axoneme Photoreceptor Connecting Cilium
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Chromatin Binding Sequence-specific DNA Binding Protein Dimerization Activity E-box Binding	Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Embryo Development Tissue Development Retina Layer Formation Cerebellum Development Pancreas Development Exocrine Pancreas Development Endocrine Pancreas Development Amacrine Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Retinoic Acid Receptor Signaling Pathway Neuron Fate Commitment Regulation Of Neural Retina Development	Visual Perception Eye Photoreceptor Cell Development Response To Stimulus Retina Development In Camera-type Eye
Pathways		Regulation of beta-cell development Regulation of gene expression in early pancreatic precursor cells
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: AAMP CCDC27 CCNDBP1 KAT2B RBPJ RPGRIP1 SPATA7 TCF12 TCF4 TRIP12 ZW10	24 interactors: AEN BRCA1 CBX8 CCDC146 CHCHD3 CSPP1 DPPA4 FAM74A4 FEM1C GATAD2B HEYL IQCE MAGEB2 NPHP4 PTF1A RPGR RPP25L SCNM1 TBC1D7 TFPT TRIB3 ZNF337 ZNF417 ZNF564
Entrez ID		256297	57096
HPRD ID		09526	05673
Ensembl ID		ENSG00000168267	ENSG00000092200
Uniprot IDs		Q7RTS3	Q96KN7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gluconeogenesis Transcription Initiation From RNA Polymerase II Promoter Regulation Of Glycoprotein Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Glucose Metabolic Process Myoblast Differentiation Regulation Of Gluconeogenesis Pituitary Gland Development Transcription From RNA Polymerase II Promoter Somatic Stem Cell Maintenance Regulation Of Cell Cycle Protein Localization To Photoreceptor Outer Segment Positive Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Positive Regulation Of Ephrin Receptor Signaling Pathway Arterial Endothelial Cell Fate Commitment Epidermal Cell Fate Specification Protein Localization To Photoreceptor Connecting Cilium Regulation Of BMP Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Diencephalon Development Negative Regulation Of Cell Cycle Regulation Of Organ Growth Histone H3-K9 Acetylation Regulation Of Protein ADP-ribosylation Blood Vessel Lumenization Catenin Import Into Nucleus Blood Vessel Endothelial Cell Fate Specification Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Glucose Metabolic Process Muscle Structure Development Blood Vessel Development Protein Localization To Organelle Vasculature Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Negative Regulation Of Histone H2A K63-linked Ubiquitination Protein Localization To Nonmotile Primary Cilium N-terminal Peptidyl-lysine Acetylation Endothelial Cell Fate Specification Regulation Of Striated Muscle Tissue Development Notch Signaling Pathway Positive Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Maintenance Of DNA Repeat Elements Clara Cell Differentiation Cell Cycle Arrest Stem Cell Maintenance Regulation Of Carbohydrate Metabolic Process Interleukin-4 Secretion	Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Fatty Acid Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Apoptotic Signaling Pathway Negative Regulation Of Fatty Acid Metabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Intrinsic Apoptotic Signaling Pathway Regulation Of Protein Ubiquitination Negative Regulation Of Lipid Biosynthetic Process Photoreceptor Cell Development Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Androgen Receptor Activity Negative Regulation Of Lipid Metabolic Process Regulation Of Fatty Acid Metabolic Process Regulation Of Cellular Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Neural Retina Development Negative Regulation Of Cilium Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Eye Development Signal Transduction By P53 Class Mediator Amacrine Cell Differentiation Cellular Response To Indole-3-methanol
Tagcloud ?		anlage atohla augmentation cerebellar fertilization granule hepatocyte hpf inc klf8 kruppel lip met modulates morphants morpholino mosp neurobiol periodicals perturbed primordium purkinje rescued rhombic rhombomere substantially tectum wiley zebrafish	ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cep76 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 tgl throw ttl
Tagcloud (Difference) ?		anlage atohla augmentation cerebellar fertilization granule hepatocyte hpf inc klf8 kruppel lip met modulates morphants morpholino mosp neurobiol periodicals perturbed primordium purkinje rescued rhombic rhombomere substantially tectum wiley zebrafish	ahi1 bardet biedl c2cd3 cc2d2a cc2d2b ccdc135 cep76 cilia ciliogenesis ciliopathies dyneins gruber jbts jouberin joubert meckel midasins mks mks6 moxr nephronophthisis nphp nphp1 nphp4 tgl throw ttl
Tagcloud (Intersection) ?